Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2000-5-18
pubmed:abstractText
The lung is protected by an array of interacting defense mechanisms.These include mechanical defenses that filter and remove particulates from the inhaled air as well as mechanisms to capture and remove particulates that penetrate into the lung as well as chemical and cellular defenses that can kill invading microorganisms. Optimal lung defense requires coordinated action of these various defenses. However, whereas failure of any defense mechanism increases the risk of infection, the various mechanisms provide, at least to a certain extent, redundant protection. As a result, many individuals with compromise of a single defense mechanism may not become clinically ill. Syndromes characterized by chronic infection of the lower respiratory tract are therefore associated with several defects in respiratory tract defense.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0882-0546
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7-13
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Host defenses and pathogenesis.
pubmed:affiliation
Department of Internal Medicine, University of Nebraska Medical Center, Omaha 68198-5300, USA.
pubmed:publicationType
Journal Article, Review