Linked Life Data

10748599

Source:http://linkedlifedata.com/resource/pubmed/id/10748599

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2000-5-3
pubmed:abstractText
Both Kraepelin and E. Bleuler reported that nonspecific symptoms are frequently present before the first psychotic symptoms manifest. In the ABC schizophrenia study, we were able to show that, in three-quarters of the cases, initial psychotic symptoms are preceded by a prodromal phase of several years standing that begins with non-specific signs such as negative and depressive symptoms. These early symptoms lead to social disabilities that--already before the onset of acute psychotic symptoms--have an adverse effect on the life situation of those who subsequently go on to develop schizophrenia. With the aim of preventing these early social consequences, patients at risk of developing schizophrenia should be identified in good time, and referred to early detection/intervention centers for a diagnostic work-up. In addition to the initial, non-specific symptoms that mark the beginning of the prodromal phase, basic disturbances also need to be considered, since they have considerable prognostic importance for the transition to psychosis. Other factors of importance are retarded development and behavioral anomalies in childhood and familial load, since premorbid risk factors are indicative of a congenital psychotic risk.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1438-3276
pubmed:author
pubmed:issnType
Print
pubmed:day
9
pubmed:volume
142
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
26-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
[Long prodromal phase in schizophrenia. By recognizing it, the prognosis of the patient can be significantly improved].
pubmed:affiliation
Zentralinstitut für Seelische Gesundheit, Arbeitsgruppe Schizophrenjeforschung, Mannheim.
pubmed:publicationType
Journal Article, English Abstract, Review