Source:http://linkedlifedata.com/resource/pubmed/id/10748422
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2000-5-2
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pubmed:abstractText |
Optically enhanced NMR with (129)Xe and (3)He is emerging as a novel and promising technique for medical imaging of lungs and other tissues. Here it is shown that hyperpolarized (129)Xe NMR provides a powerful means of measuring blood oxygenation quantitatively and noninvasively. The interaction of xenon with hemoglobin is responsible for an oxygen-dependent NMR shift of (129)Xe in red blood cells, in sharp contrast to the current model of xenon-hemoglobin binding. This effect could be exploited in brain functional studies, and in the assessment of conditions and diseases affected by blood oxygenation.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0740-3194
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
491-6
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10748422-Humans,
pubmed-meshheading:10748422-Image Enhancement,
pubmed-meshheading:10748422-Magnetic Resonance Spectroscopy,
pubmed-meshheading:10748422-Optics and Photonics,
pubmed-meshheading:10748422-Oxygen,
pubmed-meshheading:10748422-Oxygen Consumption,
pubmed-meshheading:10748422-Sensitivity and Specificity,
pubmed-meshheading:10748422-Xenon Radioisotopes
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pubmed:year |
2000
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pubmed:articleTitle |
Hyperpolarized 129Xe NMR as a probe for blood oxygenation.
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pubmed:affiliation |
CRC Clinical Magnetic Resonance Research Group, Institute of Cancer Research, The Royal Marsden NHS Trust, Sutton, Surrey, UK.
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pubmed:publicationType |
Journal Article
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