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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2000-6-13
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pubmed:abstractText |
The synthesis and in vitro evaluation of the acetamidine derivatives of hetero-substituted lysine and homolysine analogues have identified potent inhibitors of human nitric oxide synthase enzymes, including examples with marked selectivity for the inducible isoform.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Acetamides,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Indicators and Reagents,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Lysine,
http://linkedlifedata.com/resource/pubmed/chemical/NOS2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Ornithine,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfides,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfones
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0960-894X
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pubmed:author |
pubmed-author:BeamsR MRM,
pubmed-author:CarterKK,
pubmed-author:ChambersC LCL,
pubmed-author:ClarkH AHA,
pubmed-author:DaviesP IPI,
pubmed-author:DawsonJJ,
pubmed-author:DrysdaleM JMJ,
pubmed-author:FranzmanK WKW,
pubmed-author:FrenchCC,
pubmed-author:HodgsonS TST,
pubmed-author:HodsonH FHF,
pubmed-author:KleanthousSS,
pubmed-author:KnowlesR GRG,
pubmed-author:RiderPP,
pubmed-author:SandersDD,
pubmed-author:SawyerD ADA,
pubmed-author:ScottK JKJ,
pubmed-author:ShearerB GBG,
pubmed-author:SmithSS,
pubmed-author:StockerRR,
pubmed-author:TOSS,
pubmed-author:TackleyM CMC,
pubmed-author:YoungR JRJ
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pubmed:issnType |
Print
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pubmed:day |
20
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
597-600
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pubmed:dateRevised |
2011-10-27
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pubmed:meshHeading |
pubmed-meshheading:10741561-Acetamides,
pubmed-meshheading:10741561-Enzyme Inhibitors,
pubmed-meshheading:10741561-Humans,
pubmed-meshheading:10741561-Indicators and Reagents,
pubmed-meshheading:10741561-Isoenzymes,
pubmed-meshheading:10741561-Lysine,
pubmed-meshheading:10741561-Nitric Oxide Synthase,
pubmed-meshheading:10741561-Nitric Oxide Synthase Type II,
pubmed-meshheading:10741561-Ornithine,
pubmed-meshheading:10741561-Sulfides,
pubmed-meshheading:10741561-Sulfones
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pubmed:year |
2000
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pubmed:articleTitle |
Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine.
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pubmed:affiliation |
Glaxo Wellcome Research and Development, Stevenage, Hertfordshire, UK. rjy40958@glaxowellcome.co.uk
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pubmed:publicationType |
Journal Article
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