Source:http://linkedlifedata.com/resource/pubmed/id/10741515
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2000-5-10
|
| pubmed:abstractText |
The objective of this prospective study was to determine if bone densitometry can detect disparities in regional adaptive bone remodelling surrounding the cementless porous-coated femoral component of a hip prosthesis in two titanium alloy implants of different design . These prostheses were the S-ROM (n=69) and the Multilock (n=65). The Multilock implants consisted of two groups; 25 had a 50 micron layer of hydroxyapatite (HA) sprayed over the porous surface of the femoral component and the remaining 40 femoral components were not coated with HA. Densitometry was performed with dual energy X-ray absorptiometry (DXA) utilizing the LUNAR ORTHO software to analyse the seven Gruen zones. Bone mineral density measurements were obtained within a week of surgery as a baseline reference and at 6, 12, 24, 36 and 48 months thereafter. At 6 months there was significant mineral loss in all Gruen zones in the three prostheses. By 48 months there were differences in mineral loss between the three prostheses. In the zones adjacent to the porous surface, predominantly zones 1 and 7, the S-ROM exhibited 60% less mineral loss than the Multilock in zone 1, and there was no significant difference in zone 7. Compared to the Multilock-HA, the S-ROM lost 35% less mineral in zone 1, but the Multilock lost 70% less mineral than the S-ROM in zone 7. The Multilock-HA lost 37% and 75% less mineral than the Multilock in zones 1 and 7, respectively, i.e., hydroxyapatite coating tended to preserve bone stalk. Using the Gruen zone area measurements provided by the software, the S-ROM had significantly greater bone resorption in zone 7 at 24 months than either of the Multilocks, which did not differ from each other. In conclusion, DXA has shown differences in periprosthetic adaptive bone remodelling between implants of different design and composition as a function of time.
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| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0341-2695
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
23
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
325-9
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| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:10741515-Absorptiometry, Photon,
pubmed-meshheading:10741515-Adult,
pubmed-meshheading:10741515-Aged,
pubmed-meshheading:10741515-Aged, 80 and over,
pubmed-meshheading:10741515-Biomechanics,
pubmed-meshheading:10741515-Bone Density,
pubmed-meshheading:10741515-Bone Remodeling,
pubmed-meshheading:10741515-Coated Materials, Biocompatible,
pubmed-meshheading:10741515-Durapatite,
pubmed-meshheading:10741515-Female,
pubmed-meshheading:10741515-Femur,
pubmed-meshheading:10741515-Hip Prosthesis,
pubmed-meshheading:10741515-Humans,
pubmed-meshheading:10741515-Male,
pubmed-meshheading:10741515-Middle Aged,
pubmed-meshheading:10741515-Porosity,
pubmed-meshheading:10741515-Prospective Studies,
pubmed-meshheading:10741515-Prosthesis Design,
pubmed-meshheading:10741515-Software,
pubmed-meshheading:10741515-Titanium
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
Bone densitometry: influence of prosthetic design and hydroxyapatite coating on regional adaptive bone remodelling.
|
| pubmed:affiliation |
McGill University Health Center, MGH, Montreal, Canada. rosenthl@rad.mgh.mcgill.ca
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|