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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2000-4-14
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pubmed:abstractText |
Cell proliferation, vector titer and accessibility of target cells represent hurdles for efficient gene transfer to lung epithelia in vivo using recombinant murine leukemia (MuLV)-based retroviruses. We tested the hypothesis that the pulmonary epithelium is susceptible to retroviral-mediated gene transfer when stimulated to proliferate by a mitogen, keratinocyte growth factor (KGF).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/FGF10 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/FGF7 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Fgf10 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Fgf10 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Fgf7 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Fgf7 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factor 10,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factor 7,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Growth Substances,
http://linkedlifedata.com/resource/pubmed/chemical/Proliferating Cell Nuclear Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Virus,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/beta-Galactosidase,
http://linkedlifedata.com/resource/pubmed/chemical/leukemia virus receptor, gibbon ape
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pubmed:status |
MEDLINE
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pubmed:issn |
1099-498X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
22-30
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10738582-Animals,
pubmed-meshheading:10738582-Cell Division,
pubmed-meshheading:10738582-Cell Polarity,
pubmed-meshheading:10738582-Epithelial Cells,
pubmed-meshheading:10738582-Fibroblast Growth Factor 10,
pubmed-meshheading:10738582-Fibroblast Growth Factor 7,
pubmed-meshheading:10738582-Fibroblast Growth Factors,
pubmed-meshheading:10738582-Gene Transfer Techniques,
pubmed-meshheading:10738582-Genetic Vectors,
pubmed-meshheading:10738582-Growth Substances,
pubmed-meshheading:10738582-Humans,
pubmed-meshheading:10738582-Leukemia Virus, Murine,
pubmed-meshheading:10738582-Lung,
pubmed-meshheading:10738582-Mice,
pubmed-meshheading:10738582-Proliferating Cell Nuclear Antigen,
pubmed-meshheading:10738582-Rats,
pubmed-meshheading:10738582-Rats, Sprague-Dawley,
pubmed-meshheading:10738582-Receptors, Virus,
pubmed-meshheading:10738582-Recombinant Proteins,
pubmed-meshheading:10738582-beta-Galactosidase
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pubmed:articleTitle |
Keratinocyte growth factor induced epithelial proliferation facilitates retroviral-mediated gene transfer to distal lung epithelia in vivo.
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pubmed:affiliation |
Department of Pediatrics, University of Iowa College of Medicine, Iowa City 52242, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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