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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2000-4-26
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pubmed:abstractText |
Human RBC metabolism is modulated by the cell oxygenation state. Among other mechanisms, competition of deoxyhemoglobin and some glycolytic enzymes for the cytoplasmic domain of band 3 is probably involved in modulation. This metabolic modulation is connected to variations in intracellular NADPH and ATP levels as a function of the oxygenation state of the cell, and, consequently, it should have physiologic relevance. The present study investigates the effect of storage on this metabolic modulation and its relationship with the alteration of membrane protein composition.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0041-1132
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
353-60
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10738039-Adenine,
pubmed-meshheading:10738039-Blood Banks,
pubmed-meshheading:10738039-Blood Preservation,
pubmed-meshheading:10738039-Cell Survival,
pubmed-meshheading:10738039-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:10738039-Erythrocytes,
pubmed-meshheading:10738039-Extracellular Space,
pubmed-meshheading:10738039-Glucose,
pubmed-meshheading:10738039-Humans,
pubmed-meshheading:10738039-Mannitol,
pubmed-meshheading:10738039-Membrane Proteins,
pubmed-meshheading:10738039-Oxygen,
pubmed-meshheading:10738039-Pentose Phosphate Pathway,
pubmed-meshheading:10738039-Potassium,
pubmed-meshheading:10738039-Sodium,
pubmed-meshheading:10738039-Sodium Chloride,
pubmed-meshheading:10738039-Sodium Dodecyl Sulfate
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pubmed:year |
2000
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pubmed:articleTitle |
Blood bank conditions and RBCs: the progressive loss of metabolic modulation.
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pubmed:affiliation |
Institute of Chemistry and Clinical Chemistry, Faculty of Medicine, Catholic University, Rome, Italy. i.messana@uniserv.ccr.rm.cnr.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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