Linked Life Data

10732952

Source:http://linkedlifedata.com/resource/pubmed/id/10732952

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2000-4-11
pubmed:abstractText
The concentrations of codeine ([C]) and morphine ([M]) excreted in urine obtained from nine subjects at various time intervals after the ingestion of 10-40 mg of both simple and compound codeine doses three times per day for three days were determined by gas chromatography-mass spectrometry analysis. Four distinct [C]/[M] distribution patterns (phases) were observed: a, [C] > [M] from ingestion of first dose to 78-108 h after ingestion of the first dose (18-48 h after the ingestion of the last dose); b, [C] approximately [M] 78-90 h after ingestion of the first dose (18-30 h after ingestion of the last dose); c, [C] < [M] 78-102 h after ingestion of first dose (18-42 h after ingestion of the last dose); and d, [C] <0.05 microg/mL and [M] > 0.05 microg/mL 84-96 h after ingestion of the first dose (24-36 h after ingestion of the last dose with [M] ranging from 0.10 to 0.30 microg/mL) toward the terminal phase. No single individual exhibited all four [C]/[M] distribution characteristics during the entire excretion period and intervals monitored in this study. These data are of reference value for differentiating codeine and morphine/heroin ingestion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0146-4760
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
133-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Urinary excretion of codeine and morphine following the administration of codeine-containing cold syrup.
pubmed:affiliation
National Laboratories of Foods and Drugs, Department of Health, Taipei, Taiwan.
pubmed:publicationType
Journal Article