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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5461
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pubmed:dateCreated |
2000-3-30
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pubmed:abstractText |
The fly Drosophila melanogaster is one of the most intensively studied organisms in biology and serves as a model system for the investigation of many developmental and cellular processes common to higher eukaryotes, including humans. We have determined the nucleotide sequence of nearly all of the approximately 120-megabase euchromatic portion of the Drosophila genome using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map. Efforts are under way to close the remaining gaps; however, the sequence is of sufficient accuracy and contiguity to be declared substantially complete and to support an initial analysis of genome structure and preliminary gene annotation and interpretation. The genome encodes approximately 13,600 genes, somewhat fewer than the smaller Caenorhabditis elegans genome, but with comparable functional diversity.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0036-8075
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pubmed:author |
pubmed-author:WangZ YZY,
pubmed-author:SaundersR DRD,
pubmed-author:AdamsM DMD,
pubmed-author:TurnerRR,
pubmed-author:AshburnerMM,
pubmed-author:WangA HAH,
pubmed-author:DaviesPP,
pubmed-author:NelsonD LDL,
pubmed-author:EvansC ACA,
pubmed-author:NelsonD RDR,
pubmed-author:HanJJ,
pubmed-author:HOSS,
pubmed-author:SpiesFF,
pubmed-author:FerrasJJ,
pubmed-author:MorrisJJ,
pubmed-author:PollardJJ,
pubmed-author:DurbinK JKJ,
pubmed-author:VenterJ CJC,
pubmed-author:WeiM HMH,
pubmed-author:HarveyDD,
pubmed-author:LeaAA,
pubmed-author:WuDD,
pubmed-author:PanSS,
pubmed-author:RubinG MGM,
pubmed-author:WeissenbachJJ,
pubmed-author:MurphyBB,
pubmed-author:WilliamsS MSM,
pubmed-author:SmithTT,
pubmed-author:MASS,
pubmed-author:SpradlingA CAC,
pubmed-author:StrongRR,
pubmed-author:YangSS,
pubmed-author:ZhouXX,
pubmed-author:GelbartW MWM,
pubmed-author:LewisS ESE,
pubmed-author:OOIS KSK,
pubmed-author:SmithH OHO,
pubmed-author:LimPP,
pubmed-author:RiceC PCP,
pubmed-author:LiangYY,
pubmed-author:ButlerHH,
pubmed-author:HarrisMM,
pubmed-author:PalazzoloMM,
pubmed-author:DownerRR,
pubmed-author:SimpsonMM,
pubmed-author:BotchanM RMR,
pubmed-author:ZiaMM,
pubmed-author:MurphyLL,
pubmed-author:StapletonMM,
pubmed-author:WeinstockG MGM,
pubmed-author:ShenHH,
pubmed-author:SunEE,
pubmed-author:NelsonK AKA,
pubmed-author:GlassenGG,
pubmed-author:BaldwinDD,
pubmed-author:KraftCC,
pubmed-author:BurtisK CKC,
pubmed-author:DunnPP,
pubmed-author:MoyMM,
pubmed-author:LieAA,
pubmed-author:Goi?AA,
pubmed-author:DengZZ,
pubmed-author:BasuAA,
pubmed-author:HarrisN LNL,
pubmed-author:SchererS ESE,
pubmed-author:ReeseM GMG,
pubmed-author:RichardsSS,
pubmed-author:HoustonK AKA,
pubmed-author:JalaliMM,
pubmed-author:DoyleCC,
pubmed-author:CherryJ MJM,
pubmed-author:LamVV,
pubmed-author:HernandezJ RJR,
pubmed-author:ZinKK,
pubmed-author:ChandraII,
pubmed-author:MatteiBB,
pubmed-author:McPhersonDD,
pubmed-author:NixonKK,
pubmed-author:SuttonG GGG
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