Linked Life Data

10729633

Source:http://linkedlifedata.com/resource/pubmed/id/10729633

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2000-5-23
pubmed:abstractText
Expression pattern of peroxiredoxin I (Prx I), a novel stress-inducible 23 kDa protein, initially found in macrophages, was investigated in the normal rat nervous system by western blot and immunohistochemistry. The protein was widely expressed in the central and peripheral nervous system, particularly in oligodendroglia and Schwann cells. Weak staining of axons and neuropil suggests neuronal processes also may contain Prx I. Immunostaining of neuronal cell bodies were not evident. Since Prx I reduces hydrogen peroxide, the widespread glial expression of Prx I indicates that it may play an important protective role against oxidative damage in the nervous system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
283
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-60
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Peroxiredoxin I (macrophage 23 kDa stress protein) is highly and widely expressed in the rat nervous system.
pubmed:affiliation
Department of Neurology and Neurological Science, Tokyo Medical and Dental University, Graduate School of Medicine, 1-5-45 Yushima, Bunkyo-ku, 113-8519, Tokyo, Japan. h-mizusawa.nuro@med.tmd.ac.jp
pubmed:publicationType
Journal Article