Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-3-31
pubmed:abstractText
This study was undertaken to determine the prognostic significance of hypotension induced during preoperative dobutamine stress echocardiography (DSE) before vascular and noncardiac thoracic surgery. Wall motion abnormality during DSE predicts perioperative risk. Although hypotension during DSE has not been shown to correlate with the presence or severity of coronary artery disease, its significance in perioperative risk assessment is unknown. We retrospectively studied 300 patients who had DSE within 6 months of noncardiac surgery. Perioperative events including death, myocardial infarction, ischemia, and arrhythmias were recorded. Odds ratios with 95% confidence intervals were used to examine the association between clinical and echocardiographic variables and perioperative events. A hypotensive response during DSE was seen in 85 patients (28%). Forty-eight patients (16%) had 54 perioperative complications including 4 cardiac-related deaths, 10 myocardial infarctions, 12 myocardial ischemic events, and 28 arrhythmias. Hypotension during DSE was predictive of the combined end point of perioperative cardiac mortality, myocardial infarction, and ischemia (odds ratio 4.04, 95% confidence interval 1.72 to 9.51). In a multivariate logistic regression model, hypotension during DSE remained a significant predictor (odds ratio 4.10, p<0.01). DSE-related hypotension was predictive of perioperative cardiac events and therefore may have a role in risk stratification before vascular or noncardiac thoracic surgery.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0002-9149
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
85
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
478-83
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:10728954-Adult, pubmed-meshheading:10728954-Aged, pubmed-meshheading:10728954-Aged, 80 and over, pubmed-meshheading:10728954-Blood Pressure, pubmed-meshheading:10728954-Cardiotonic Agents, pubmed-meshheading:10728954-Coronary Disease, pubmed-meshheading:10728954-Dobutamine, pubmed-meshheading:10728954-Echocardiography, pubmed-meshheading:10728954-Exercise Test, pubmed-meshheading:10728954-Female, pubmed-meshheading:10728954-Humans, pubmed-meshheading:10728954-Hypotension, pubmed-meshheading:10728954-Infusions, Intravenous, pubmed-meshheading:10728954-Male, pubmed-meshheading:10728954-Middle Aged, pubmed-meshheading:10728954-Odds Ratio, pubmed-meshheading:10728954-Prognosis, pubmed-meshheading:10728954-Retrospective Studies, pubmed-meshheading:10728954-Ventricular Dysfunction, Left
pubmed:year
2000
pubmed:articleTitle
Usefulness of hypotension during dobutamine echocardiography in predicting perioperative cardiac events.
pubmed:affiliation
Department of Emergency Medicine, University of Michigan Medical Center, Ann Arbor, USA.
pubmed:publicationType
Journal Article, Comparative Study