Linked Life Data

10726998

Source:http://linkedlifedata.com/resource/pubmed/id/10726998

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2000-4-11
pubmed:databankReference
pubmed:abstractText
The sequence of the cDNA of the histone H4 gene of Leishmania tarentolae is reported herein. The predicted 100-amino-acid-long protein has the highest degree of identity with the histone H4 gene of L. infantum and shares with it a 5' region that shows a very low degree of identity with the corresponding region of histone H4 genes from other organisms. However, between these two genes is a 7.7% nucleotide difference that results in seven different amino acids, located in the 5', central, and 3' regions of the coding sequence. Such a divergence in the H4 gene, which is considered to be one of the most highly conserved genes, between closely related members of the genus Leishmania is unexpected and may reflect some unusual features of these important proteins in kinetoplastid flagellates.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0932-0113
pubmed:author
pubmed:issnType
Print
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
259-61
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Unexpectedly high variability of the histone H4 gene in Leishmania.
pubmed:affiliation
Department of Biology, University of California, Riverside 92521, USA. jula@paru.cas.cz
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't