Linked Life Data

10725188

Source:http://linkedlifedata.com/resource/pubmed/id/10725188

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-5-15
pubmed:abstractText
To assess the effect of various analysis parameters on the sensitivity of event-related fMRI analyses, 36 analyses were performed on a single fMRI data-set, varying parameters along four axes: (1) resampled voxel size; (2) spatial smoothing; (3) temporal smoothing; and (4) the set of basis functions used to model event-related responses. Sensitivity (i.e., the probability of detecting an activation given it exists) was assessed in terms of Z scores and by a metric for corrected P values, the negative log of the expected Euler characteristic. Sixteen brain regions distributed across cortical and subcortical areas were included in the meta-analysis. Main effects on sensitivity were found for resampled voxel size, spatial smoothing, temporal smoothing, and the set of basis functions chosen. The analysis parameters that generally produced the most sensitive analyses were a 2-mm(3) resampled voxel size, 10-mm spatial smoothing, 4-s temporal smoothing, and a basis set comprising a hemodynamic response function and its temporal derivative.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1053-8119
pubmed:author
pubmed:copyrightInfo
Copyright 2000 Academic Press.
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
326-33
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
A study of analysis parameters that influence the sensitivity of event-related fMRI analyses.
pubmed:affiliation
The Psychology Department and Center for Neuroscience, University of California, Davis, California 95616, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't