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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2000-4-13
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pubmed:databankReference |
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068303,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068304,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068305,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068306,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068307,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068308,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068309,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068310,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068311,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068312,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068313,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068314,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068315,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068316,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AF068317
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pubmed:abstractText |
Allelic diversity has been examined from a variety of Mus musculus subspecies and Mus spretus strains by sequencing at a 453-bp unique sequence locus. One M. m. domesticus classic inbred strain, C57BL/KsJ, contained a sequence identical to that in the M. spretus wild-derived inbred strain SEG, and other wild M. spretus isolates. Such a result should have been precluded by the expected divergence between the species unless there has been interspecies gene flow. Examination of C57BL/KsJ for M. spretus-specific repetitive sequences shows that it is neither a mis-identified spretus strain nor a domesticus/spretus hybrid. Thus, in addition to the previously reported presence of small amounts of Mus spretus-specific repetitive DNA in M. m. domesticus, there is a detectable flow of unique sequence between the two species. There was also ancestral polymorphism observed among the spretus alleles. The difficulty of distinguishing ancestral polymorphism from horizontal transfer is discussed.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0938-8990
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
225-30
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10723728-Alleles,
pubmed-meshheading:10723728-Animals,
pubmed-meshheading:10723728-Base Sequence,
pubmed-meshheading:10723728-DNA,
pubmed-meshheading:10723728-Evolution, Molecular,
pubmed-meshheading:10723728-Genetic Variation,
pubmed-meshheading:10723728-Mice,
pubmed-meshheading:10723728-Mice, Inbred C57BL,
pubmed-meshheading:10723728-Mice, Inbred CBA,
pubmed-meshheading:10723728-Molecular Sequence Data,
pubmed-meshheading:10723728-Muridae,
pubmed-meshheading:10723728-Phylogeny,
pubmed-meshheading:10723728-Sequence Alignment,
pubmed-meshheading:10723728-Sequence Analysis, DNA,
pubmed-meshheading:10723728-Species Specificity
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pubmed:year |
2000
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pubmed:articleTitle |
Gene flow of unique sequences between Mus musculus domesticus and Mus spretus.
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pubmed:affiliation |
Department of Biochemistry, University of Texas Health Science Center, San Antonio 78284-7760, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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