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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2000-5-18
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pubmed:abstractText |
Transforming growth factor-beta 1 (TGF-beta 1) plays a central role in the pathogenesis of renal fibrosis. In contrast, hepatocyte growth factor (HGF) may be an important molecule for tissue repair. As TGF-beta 1 is a suppressor molecule for HGF expression, we asked whether a decrease in HGF expression would be accompanied by an increase in TGF-beta 1 and whether the progression of renal fibrosis would be modulated.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
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pubmed:status |
MEDLINE
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|
pubmed:month |
Mar
|
|
pubmed:issn |
0085-2538
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
937-48
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10720947-Animals,
pubmed-meshheading:10720947-Apoptosis,
pubmed-meshheading:10720947-Cell Division,
pubmed-meshheading:10720947-Extracellular Matrix,
pubmed-meshheading:10720947-Fibrosis,
pubmed-meshheading:10720947-Glomerulonephritis,
pubmed-meshheading:10720947-Hepatocyte Growth Factor,
pubmed-meshheading:10720947-Humans,
pubmed-meshheading:10720947-Immunoglobulin G,
pubmed-meshheading:10720947-Kidney,
pubmed-meshheading:10720947-Kidney Tubules,
pubmed-meshheading:10720947-Mice,
pubmed-meshheading:10720947-Phenotype,
pubmed-meshheading:10720947-Recombinant Proteins,
pubmed-meshheading:10720947-Transforming Growth Factor beta
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pubmed:year |
2000
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pubmed:articleTitle |
Reciprocal balance of hepatocyte growth factor and transforming growth factor-beta 1 in renal fibrosis in mice.
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pubmed:affiliation |
Department of Oncology, Biomedical Research Center, Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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