Linked Life Data

10720572

Source:http://linkedlifedata.com/resource/pubmed/id/10720572

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2000-5-10
pubmed:databankReference
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666547, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666548, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666549, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666550, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666551, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666552, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666553, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666554, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666555, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666556, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666557, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666558, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666559, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666560, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666561, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666562, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666563, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666564, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666565, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666566, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666567, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666568, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666569, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666570, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666571, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666572, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666573, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666574, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666575, http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AQ666576
pubmed:abstractText
To clone the goat Polled Intersex Syndrome (PIS) gene(s), a chromosome walk was performed from six entry points at 1q43. This enabled 91 BACs to be recovered from a recently constructed goat BAC library. Six BAC contigs of goat chromosome 1q43 (ICC1-ICC6) were thus constructed covering altogether 4.5 Mb. A total of 37 microsatellite sequences were isolated from this 4.5-Mb region (16 in this study), of which 33 were genotyped and mapped. ICC3 (1500 kb) was shown by genetic analysis to encompass the PIS locus in a approximately 400-kb interval without recombinants detected in the resource families (293 informative meioses). A strong linkage disequilibrium was detected among unrelated animals with the two central markers of the region, suggesting a probable location for PIS in approximately 100 kb. High-resolution comparative mapping with human data shows that this DNA segment is the homolog of the human region associated with Blepharophimosis Ptosis Epicanthus inversus Syndrome (BPES) gene located in 3q23. This finding suggests that homologous gene(s) could be responsible for the pathologies observed in humans and goats.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-10036183, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-10191085, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-10197976, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-10341090, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-10430929, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-1673956, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-2030730, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-5770278, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-6613996, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-7566096, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-7887434, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-7928389, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-7990924, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-8111369, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-8348155, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-8533086, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-8570694, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-8625802, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-8835530, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-8878693, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-9166589, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-9457672, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-9750190, http://linkedlifedata.com/resource/pubmed/commentcorrection/10720572-9770501
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1088-9051
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
311-8
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
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