Linked Life Data

10716537

Source:http://linkedlifedata.com/resource/pubmed/id/10716537

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2000-5-15
pubmed:abstractText
Exposure to novel males can disrupt intrauterine implantation of fertilized ova in inseminated female mice, an effect established to involve androgen-dependent male excretions. These experiments were designed to examine potential roles of vesicular and coagulating glands, independently or in conjunction with preputial glands. Inseminated females were randomly assigned to conditions of housing below (1) no males; (2) males with vesicular-coagulating gland removal; (3) males with preputial, vesicular, and coagulating gland removal; or (4) males subjected to sham surgery. Males with accessory glands removed disrupted pregnancy to the same extent as did sham-operated males. Long-term testosterone replacement permitted pregnancy disruption in castrated males with vesicular-coagulating and preputial glands removed. Fertility was not disrupted by preputialectomy, but half of the males without vesicular-coagulating glands could not inseminate females. We suggest that males' capacity to disrupt pregnancy could derive from androgen metabolism that is independent of actions on major accessory glands.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0031-9384
pubmed:author
pubmed:issnType
Print
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
285-90
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Novel male mice disrupt pregnancy despite removal of vesicular-coagulating and preputial glands.
pubmed:affiliation
Department of Psychology, McMaster University, Hamilton, Ontario, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't