Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1977-4-28
|
| pubmed:abstractText |
1. Limited coagulations of the locus coeruleus and subcoeruleus nuclei have been performed in rats and the sleep-waking cycle was continuously monitored during 9 days. The cortical and diencephalic noradrenaline content was mesured at the termination of the experiment, on the 10th post lesion day. 2. The bilateral destruction of the locus coeruleus is followed by the appearance of a uro-genital syndrome consisting of hema turia, bladder distension and penile erection. The states of sleep are disturbed during the first two days (increase of slow-wave sleep and decrease of paradoxical sleep times) and thereafter return to normal. Additionally, an hyperthermia appears during the third experimental day. The cortical and diencephalic noradrenaline content decrease to 70%. 3. The simultaneous lesion of both locus coeruleus and subcoeruleus nuclei is followed by the appearance of an aphagia adipsia syndrome in addition to the uro-genital syndrome. After these lesions, it is no long possible to find paradoxical sleep episodes in polygraphic recordings while the amount of slow wave sleep is normal. Cortical and diencephalic noradrenaline content decrease more than 50%. 4. In normal rats direct injection of 6 hydroxydopamine directly in both locus coeruleus and nuclei subcoeruleus had no discernable effects either on the behaviour or on the states of sleep. The cortical noradrenaline content decreased 30% below control values. 5. These results are consistent with but do not prove the hypothesis that part of the pontine tegmentum might play an important role in triggering paradoxical sleep episodes. The role of these regions in the regulation of internal temperature, food consumption and bladder motricity is also discussed.
|
| pubmed:language |
fre
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0003-9829
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
114
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
188-209
|
| pubmed:dateRevised |
2009-10-5
|
| pubmed:meshHeading |
pubmed-meshheading:1071400-Animals,
pubmed-meshheading:1071400-Disease Models, Animal,
pubmed-meshheading:1071400-Eating Disorders,
pubmed-meshheading:1071400-Hematuria,
pubmed-meshheading:1071400-Humans,
pubmed-meshheading:1071400-Male,
pubmed-meshheading:1071400-Pons,
pubmed-meshheading:1071400-Priapism,
pubmed-meshheading:1071400-Rats,
pubmed-meshheading:1071400-Sleep Disorders,
pubmed-meshheading:1071400-Sleep Stages,
pubmed-meshheading:1071400-Urinary Bladder Diseases
|
| pubmed:year |
1976
|
| pubmed:articleTitle |
[Effects of lesions in the pontine tegmentum on the sleep stages in the rat].
|
| pubmed:publicationType |
Journal Article,
English Abstract
|