rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
2000-3-23
|
pubmed:abstractText |
Gene therapy has emerged as a new form of treatment for unresectable hepatocellular carcinoma (HCC). We evaluate here the effect of IL-12 and the suicide gene thymidine kinase as single agents and in combination to treat experimental liver cancer.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0168-8278
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
32
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
279-86
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10707868-Adenoviridae,
pubmed-meshheading:10707868-Adenoviridae Infections,
pubmed-meshheading:10707868-Animals,
pubmed-meshheading:10707868-Carcinogenicity Tests,
pubmed-meshheading:10707868-Female,
pubmed-meshheading:10707868-Gene Dosage,
pubmed-meshheading:10707868-Gene Expression,
pubmed-meshheading:10707868-Gene Therapy,
pubmed-meshheading:10707868-Gene Transfer Techniques,
pubmed-meshheading:10707868-Interleukin-12,
pubmed-meshheading:10707868-Liver Neoplasms, Experimental,
pubmed-meshheading:10707868-Mice,
pubmed-meshheading:10707868-Mice, Inbred BALB C,
pubmed-meshheading:10707868-Neoplasm Transplantation,
pubmed-meshheading:10707868-Recombination, Genetic,
pubmed-meshheading:10707868-Simplexvirus,
pubmed-meshheading:10707868-Thymidine Kinase,
pubmed-meshheading:10707868-Tumor Cells, Cultured
|
pubmed:year |
2000
|
pubmed:articleTitle |
Combined gene therapy with suicide gene and interleukin-12 is more efficient than therapy with one gene alone in a murine model of hepatocellular carcinoma.
|
pubmed:affiliation |
Department of Medicine, School of Medicine and Clinica Universitaria, University of Navarra, Pamplona, Spain.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|