Source:http://linkedlifedata.com/resource/pubmed/id/10707032
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2000-5-8
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pubmed:abstractText |
In the BIGPRO 1 trial, one year of treatment with metformin in non-diabetic obese subjects with a central fat distribution had no significant effect on fasting plasma triglyceride concentration or on blood pressure despite a decrease in weight, fasting plasma insulin and glucose concentrations. To re-evaluate the effect of metformin on fasting triglyceride concentration and on blood pressure, the BIGPRO 1.2 trial included non-diabetic men (n=168) with a fasting plasma triglyceride concentration > or =1.7 and < or =6.5 mmol/l, high blood pressure (systolic > or =140 and < or =180 and/or diastolic > or =90 and < or =105 mmHg, or treatment for hypertension) and a waist-to-hip ratio > or =0.95.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1520-7552
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pubmed:author |
pubmed-author:AndréPP,
pubmed-author:BareJ JJJ,
pubmed-author:BensoussanJ LJL,
pubmed-author:BerechJJJr,
pubmed-author:ChapiroOO,
pubmed-author:CharlesM AMA,
pubmed-author:CohenJ MJM,
pubmed-author:EschwègeEE,
pubmed-author:GrandmottetPP,
pubmed-author:IsnardFF,
pubmed-author:Juhan-VagueII,
pubmed-author:SafarMM,
pubmed-author:VaguePP
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pubmed:copyrightInfo |
Copyright 2000 John Wiley & Sons, Ltd.
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pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10707032-Adipose Tissue,
pubmed-meshheading:10707032-Adult,
pubmed-meshheading:10707032-Apolipoproteins,
pubmed-meshheading:10707032-Blood Pressure,
pubmed-meshheading:10707032-Double-Blind Method,
pubmed-meshheading:10707032-France,
pubmed-meshheading:10707032-Humans,
pubmed-meshheading:10707032-Hypertension,
pubmed-meshheading:10707032-Hypertriglyceridemia,
pubmed-meshheading:10707032-Hypoglycemic Agents,
pubmed-meshheading:10707032-Male,
pubmed-meshheading:10707032-Metformin,
pubmed-meshheading:10707032-Middle Aged,
pubmed-meshheading:10707032-Obesity,
pubmed-meshheading:10707032-Triglycerides
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pubmed:articleTitle |
Treatment with metformin of non-diabetic men with hypertension, hypertriglyceridaemia and central fat distribution: the BIGPRO 1.2 trial.
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pubmed:affiliation |
National Institute of Health and Medical Research (INSERM), unit 258, Villejuif, France. charles@vjf.inserm.fr
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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