Source:http://linkedlifedata.com/resource/pubmed/id/10706804
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2000-4-20
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pubmed:abstractText |
A one-year, prospective, two-observational cohort study was performed to evaluate the incidence and outcome in hospitalized patients (ICU and non-ICU) of nosocomial bacteraemia, and to assess its prognostic value in the ICU group. A group of 18 098 hospitalized patients and a group of 291 consecutive ICU patients were followed. Prognostic factors were determined using single and multivariable analyses. 109 (90 non-ICU and 19 ICU) patients developed 118 nosocomial bacteraemic episodes. The incidence of nosocomial bacteraemia was 6.0 per 1000 admissions (95% confidence interval (CI): 5-7%) and 65 per 1000 admissions in ICU patients (95% CI: 4.5-8.5%). Gram-positive and Gram-negative bacteria were 63/133 (47%) and 70/133 (53%) of the isolated micro-organisms respectively. Crude mortality rates were 41/109 (38%) with adverse outcome associated with mechanical ventilation (OR: 3.6; 95% CI: 1.4-9.2, P =0.01), neutropenia (OR: 7.7; 95% CI: 0.8-73.1;P =0.07) while gastro-intestinal surgery was associated with an improved outcome (OR: 0.4; 95% CI: 0.16-0.96;P =0.04). Of the 291 ICU patients, 19 acquired 22 episodes of nosocomial bacteraemia, and 18 were referred from the wards with documented nosocomial bacteraemia. Of these 37 bacteraemic patients, 17 (46%) died. When adjusting for predictors of death (SAPS II>/=40, cardiac and neurological failure), nosocomial bacteraemia markedly influence the outcome in ICU patients (OR: 3.4; 95% CI: 1.3-8.7;P =0.010). This study suggests that the outcome of nosocomial bacteraemia in hospitalized patients is poor in ventilated and neutropenic patients and that nosocomial bacteraemia per se influenced outcome in ICU patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0195-6701
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2000 The Hospital Infection Society.
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
206-13
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10706804-Aged,
pubmed-meshheading:10706804-Analysis of Variance,
pubmed-meshheading:10706804-Bacteremia,
pubmed-meshheading:10706804-Cross Infection,
pubmed-meshheading:10706804-Gastrointestinal Diseases,
pubmed-meshheading:10706804-Hospital Mortality,
pubmed-meshheading:10706804-Hospital Units,
pubmed-meshheading:10706804-Hospitals, Urban,
pubmed-meshheading:10706804-Humans,
pubmed-meshheading:10706804-Incidence,
pubmed-meshheading:10706804-Intensive Care Units,
pubmed-meshheading:10706804-Middle Aged,
pubmed-meshheading:10706804-Neutropenia,
pubmed-meshheading:10706804-Paris,
pubmed-meshheading:10706804-Predictive Value of Tests,
pubmed-meshheading:10706804-Prognosis,
pubmed-meshheading:10706804-Prospective Studies,
pubmed-meshheading:10706804-Respiration, Artificial,
pubmed-meshheading:10706804-Risk Factors,
pubmed-meshheading:10706804-Treatment Outcome
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pubmed:year |
2000
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pubmed:articleTitle |
A one-year prospective study of nosocomial bacteraemia in ICU and non-ICU patients and its impact on patient outcome.
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pubmed:affiliation |
Service de Réanimation Polyvalente, Hôpital Saint Joseph, Paris, France.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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