Source:http://linkedlifedata.com/resource/pubmed/id/10705250
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
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| pubmed:dateCreated |
2000-6-26
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| pubmed:abstractText |
Seventy-four patients who met DSM-III-R criteria for obsessive compulsive disorder (OCD) were studied in a prospective follow-up study in order to investigate course and prognosis of OCD with or without comorbid depressive symptomatology. Subjects were examined three times: at admission (baseline), 6 months later (follow-up 1) and 12 months after follow-up 1 (follow-up 2). At admission, 51 (72.9%) OCD patients were assessed as depressive by the Hamilton Depression Scale score. Between admission and follow-up 1, all patients received behavior therapy and a serotonin reuptake inhibitor, between follow-up 1 and follow-up 2 they received different kinds of treatment in order to maximize therapeutic effects. A 25% Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) score reduction from admission to follow-up 2 and in addition, a total Y-BOCS score of below 16 at follow-up 2 was defined as 'good prognosis course'. The results obtained showed that OCD patients who followed a good prognosis course, showed no significant depressive symptomatology at follow-up 2 (p = 0.001). These results imply that patients with a diagnosis of OCD may present depression at admission and/or follow-up 1; however, if OC symptomatology decreases longitudinally, depressive symptoms disappear too. We may assume that OCD is dominant over depression, and it seems that a comorbid depression does not have any major influence on the prognosis of OCD.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:issn |
0254-4962
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| pubmed:author | |
| pubmed:copyrightInfo |
Copyright 2000 S. Karger AG, Basel.
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| pubmed:issnType |
Print
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| pubmed:volume |
33
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
75-80
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:10705250-Adolescent,
pubmed-meshheading:10705250-Adult,
pubmed-meshheading:10705250-Age of Onset,
pubmed-meshheading:10705250-Aged,
pubmed-meshheading:10705250-Behavior Therapy,
pubmed-meshheading:10705250-Comorbidity,
pubmed-meshheading:10705250-Depressive Disorder,
pubmed-meshheading:10705250-Female,
pubmed-meshheading:10705250-Follow-Up Studies,
pubmed-meshheading:10705250-Humans,
pubmed-meshheading:10705250-Male,
pubmed-meshheading:10705250-Middle Aged,
pubmed-meshheading:10705250-Obsessive-Compulsive Disorder,
pubmed-meshheading:10705250-Prognosis,
pubmed-meshheading:10705250-Prospective Studies,
pubmed-meshheading:10705250-Psychiatric Status Rating Scales,
pubmed-meshheading:10705250-Retrospective Studies,
pubmed-meshheading:10705250-Serotonin Uptake Inhibitors,
pubmed-meshheading:10705250-Social Adjustment
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| pubmed:articleTitle |
Naturalistic course of obsessive compulsive disorder and comorbid depression. Longitudinal results of a prospective follow-up study of 74 actively treated patients.
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| pubmed:affiliation |
Department of Psychiatry, University of Vienna, Austria.
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| pubmed:publicationType |
Journal Article
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