Source:http://linkedlifedata.com/resource/pubmed/id/10705213
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2000-4-13
|
pubmed:abstractText |
The fetal iliac wings angle was studied in 255 fetuses before amniocentesis at 16.7 weeks (+/- 1.3), using a sonographic axial view of the fetal pelvis. The measurement could be performed in 208 fetuses (81.6%), of whom 4 had trisomy 21 (T 21). The mean iliac angle was greater in fetuses with T 21 than in normal fetuses (69.8 degrees vs. 88.7 degrees; p = 0.03). This measurement is subject to significant intra- and interexaminer variability (interclass correlation coefficient: 0.65 and 0.23, respectively). When a 90 degrees value is used as a threshold, specificity, sensitivity, positive and negative predictive values are, respectively, 80, 75, 7. 0 and 99.4%. The 20% rate of false-positives rules out the use of this measurement as the sole criterion for the indication of amniocentesis for T 21 antenatal diagnosis.
|
pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1015-3837
|
pubmed:author | |
pubmed:copyrightInfo |
Copyright 2000 S. Karger AG, Basel.
|
pubmed:issnType |
Print
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
41-5
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:10705213-Down Syndrome,
pubmed-meshheading:10705213-Female,
pubmed-meshheading:10705213-Gestational Age,
pubmed-meshheading:10705213-Humans,
pubmed-meshheading:10705213-Ilium,
pubmed-meshheading:10705213-Predictive Value of Tests,
pubmed-meshheading:10705213-Pregnancy,
pubmed-meshheading:10705213-Sensitivity and Specificity,
pubmed-meshheading:10705213-Ultrasonography, Prenatal
|
pubmed:articleTitle |
Sonographic measurement of the fetal iliac angle cannot be used alone as a marker for trisomy 21.
|
pubmed:affiliation |
Maternité Port-Royal, Hôpital Cochin, Paris, France. gilles.grange@cch.ap-hop-paris.fr
|
pubmed:publicationType |
Journal Article
|