|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1-2
|
|
pubmed:dateCreated |
2000-6-29
|
|
pubmed:abstractText |
The ectoderm of the pre-gastrula Xenopus embryo has previously been shown to be at least partially patterned along the dorsal-ventral axis. The early expression of the anti-neural homeodomain gene Dlx3 is localized to the ventral ectoderm by a mechanism that occurs prior to gastrulation and is independent of the Spemann organizer. The repression of Dlx3 is mediated by signaling though beta-catenin, but is probably not dependent on the induction of the Xnr3 or chordin genes by beta-catenin. We propose a model in which this early regulation of Dlx3 accounts for the pro-neural bias of dorsal ectoderm.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cytoskeletal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Distal-less homeobox proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Lithium Chloride,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta,
http://linkedlifedata.com/resource/pubmed/chemical/Xenopus Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Xnr3 protein, Xenopus,
http://linkedlifedata.com/resource/pubmed/chemical/Zic3 protein, Xenopus,
http://linkedlifedata.com/resource/pubmed/chemical/beta Catenin,
http://linkedlifedata.com/resource/pubmed/chemical/beta-catenin protein, Xenopus,
http://linkedlifedata.com/resource/pubmed/chemical/siamois protein, Xenopus
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0925-4773
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
1
|
|
pubmed:volume |
91
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
227-35
|
|
pubmed:dateRevised |
2006-9-29
|
|
pubmed:meshHeading |
pubmed-meshheading:10704847-Animals,
pubmed-meshheading:10704847-Cytoskeletal Proteins,
pubmed-meshheading:10704847-Ectoderm,
pubmed-meshheading:10704847-Gene Expression Regulation, Developmental,
pubmed-meshheading:10704847-Homeodomain Proteins,
pubmed-meshheading:10704847-Lithium Chloride,
pubmed-meshheading:10704847-Signal Transduction,
pubmed-meshheading:10704847-Trans-Activators,
pubmed-meshheading:10704847-Transcription Factors,
pubmed-meshheading:10704847-Transforming Growth Factor beta,
pubmed-meshheading:10704847-Xenopus Proteins,
pubmed-meshheading:10704847-Xenopus laevis,
pubmed-meshheading:10704847-beta Catenin
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Regulation of early expression of Dlx3, a Xenopus anti-neural factor, by beta-catenin signaling.
|
|
pubmed:affiliation |
Laboratory of Molecular Genetics, NICHD, NIH, Bethesda, MD 20892, USA.
|
|
pubmed:publicationType |
Journal Article
|
