| pubmed-article:10704791 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C1705135 | lld:lifeskim |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C0014116 | lld:lifeskim |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C0020740 | lld:lifeskim |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C1335823 | lld:lifeskim |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C2931019 | lld:lifeskim |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C1825023 | lld:lifeskim |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C0086296 | lld:lifeskim |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C1704608 | lld:lifeskim |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C1697272 | lld:lifeskim |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C0599956 | lld:lifeskim |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C1522408 | lld:lifeskim |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C1704806 | lld:lifeskim |
| pubmed-article:10704791 | lifeskim:mentions | umls-concept:C1100734 | lld:lifeskim |
| pubmed-article:10704791 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:10704791 | pubmed:dateCreated | 2000-4-24 | lld:pubmed |
| pubmed-article:10704791 | pubmed:abstractText | During the development of a coated ibuprofen formulation a sticking tendency occurred when applying Aquacoat ECD. This interaction indicated the formation of a eutectic mixture. The compatibility of the components of Aquacoat ECD with ibuprofen was investigated by differential scanning calorimetry. Cetyl alcohol, a stabilizing excipient in Aquacoat, was found to form a eutectic system with ibuprofen. It was characterized by the construction of a phase diagram with 33 mol% ibuprofen and an onset temperature of 40.5 degrees C. Wide-angle X-ray diffraction was used to identify the polymorphic forms of cetyl alcohol. The results confirmed the amorphous state in the aqueous dispersion in contrast to the beta(0)- and gamma(4)-polymorphs of solid cetyl alcohol. | lld:pubmed |
| pubmed-article:10704791 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10704791 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10704791 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10704791 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10704791 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10704791 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10704791 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10704791 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10704791 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10704791 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10704791 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:10704791 | pubmed:issn | 0378-5173 | lld:pubmed |
| pubmed-article:10704791 | pubmed:author | pubmed-author:SchmidSS | lld:pubmed |
| pubmed-article:10704791 | pubmed:author | pubmed-author:SchmidtP CPC | lld:pubmed |
| pubmed-article:10704791 | pubmed:author | pubmed-author:Müller-Goyman... | lld:pubmed |
| pubmed-article:10704791 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10704791 | pubmed:day | 20 | lld:pubmed |
| pubmed-article:10704791 | pubmed:volume | 197 | lld:pubmed |
| pubmed-article:10704791 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10704791 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10704791 | pubmed:pagination | 35-9 | lld:pubmed |
| pubmed-article:10704791 | pubmed:dateRevised | 2000-12-18 | lld:pubmed |
| pubmed-article:10704791 | pubmed:meshHeading | pubmed-meshheading:10704791... | lld:pubmed |
| pubmed-article:10704791 | pubmed:meshHeading | pubmed-meshheading:10704791... | lld:pubmed |
| pubmed-article:10704791 | pubmed:meshHeading | pubmed-meshheading:10704791... | lld:pubmed |
| pubmed-article:10704791 | pubmed:meshHeading | pubmed-meshheading:10704791... | lld:pubmed |
| pubmed-article:10704791 | pubmed:meshHeading | pubmed-meshheading:10704791... | lld:pubmed |
| pubmed-article:10704791 | pubmed:meshHeading | pubmed-meshheading:10704791... | lld:pubmed |
| pubmed-article:10704791 | pubmed:meshHeading | pubmed-meshheading:10704791... | lld:pubmed |
| pubmed-article:10704791 | pubmed:meshHeading | pubmed-meshheading:10704791... | lld:pubmed |
| pubmed-article:10704791 | pubmed:meshHeading | pubmed-meshheading:10704791... | lld:pubmed |
| pubmed-article:10704791 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10704791 | pubmed:articleTitle | Interactions during aqueous film coating of ibuprofen with aquacoat ECD. | lld:pubmed |
| pubmed-article:10704791 | pubmed:affiliation | Department of Pharmaceutical Technology, Eberhard-Karls-University Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany. | lld:pubmed |
| pubmed-article:10704791 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10704791 | lld:pubmed |
