Source:http://linkedlifedata.com/resource/pubmed/id/10703963
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2000-3-31
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pubmed:abstractText |
A second-derivative spectrophotometric procedure has been developed for the simultaneous determination of tinidazole (TD), furazolidone (FD) and diloxanide furoate (DF) in a commercial preparation. The method consists of the utilization of second-derivative absorption spectra of tablet extract in distilled water and then determination of the analyte concentration in the mixture was carried out using zero-crossing (ZC) and ratio-compensation (RC) techniques. Calibration graphs constructed at their wavelengths of determination were linear in the concentration range of TD (5-20 microg ml(-1)), FD (2.5-10 microg ml(-1)) and DF (7.5-15 microg ml(-1)). The results were found to be accurate and free from interference. The details of the statistical treatment of analytical data are also presented.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antiprotozoal Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/Furans,
http://linkedlifedata.com/resource/pubmed/chemical/Furazolidone,
http://linkedlifedata.com/resource/pubmed/chemical/Tablets,
http://linkedlifedata.com/resource/pubmed/chemical/Tinidazole,
http://linkedlifedata.com/resource/pubmed/chemical/diloxanide furoate
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0731-7085
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
961-8
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pubmed:dateRevised |
2000-12-18
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pubmed:meshHeading |
pubmed-meshheading:10703963-Antiprotozoal Agents,
pubmed-meshheading:10703963-Drug Combinations,
pubmed-meshheading:10703963-Furans,
pubmed-meshheading:10703963-Furazolidone,
pubmed-meshheading:10703963-Reproducibility of Results,
pubmed-meshheading:10703963-Spectrophotometry, Ultraviolet,
pubmed-meshheading:10703963-Tablets,
pubmed-meshheading:10703963-Tinidazole
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pubmed:year |
1999
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pubmed:articleTitle |
Simultaneous determination of tinidazole, furazolidone and diloxanide furoate in a combined tablet preparation by second-derivative spectrophotometry.
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pubmed:affiliation |
Department of Pharmacy, Birla Institute of Technology and Science, Pilani, Rajasthan, India. cvnp@bits-pilani.ac.in
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pubmed:publicationType |
Journal Article
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