Linked Life Data

10702888

Source:http://linkedlifedata.com/resource/pubmed/id/10702888

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2000-3-22
pubmed:abstractText
In vitro results suggest that cilostazol is metabolised by cytochrome P450 (CYP) isoforms 1A2, 2D6, 3A and 2C19. This study investigated the role of CYP3A inhibition on the metabolism of cilostazol.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0312-5963
pubmed:author
pubmed:issnType
Print
pubmed:volume
37 Suppl 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:10702888-Administration, Oral, pubmed-meshheading:10702888-Adult, pubmed-meshheading:10702888-Anti-Bacterial Agents, pubmed-meshheading:10702888-Area Under Curve, pubmed-meshheading:10702888-Aryl Hydrocarbon Hydroxylases, pubmed-meshheading:10702888-Chromatography, High Pressure Liquid, pubmed-meshheading:10702888-Cross-Over Studies, pubmed-meshheading:10702888-Cytochrome P-450 CYP3A, pubmed-meshheading:10702888-Cytochrome P-450 Enzyme System, pubmed-meshheading:10702888-Drug Interactions, pubmed-meshheading:10702888-Erythromycin, pubmed-meshheading:10702888-Half-Life, pubmed-meshheading:10702888-Humans, pubmed-meshheading:10702888-Male, pubmed-meshheading:10702888-Oxidoreductases, N-Demethylating, pubmed-meshheading:10702888-Regression Analysis, pubmed-meshheading:10702888-Tetrazoles, pubmed-meshheading:10702888-Vasodilator Agents
pubmed:year
1999
pubmed:articleTitle
Effects of CYP3A inhibition on the metabolism of cilostazol.
pubmed:affiliation
Department of Clinical Pharmacokinetics/Pharmacodynamics & Metabolism, Otsuka America Pharmaceutical, Inc., Rockville MD 20850, USA. steveb@mocr.oapi.com
pubmed:publicationType
Journal Article, Clinical Trial