|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2000-5-31
|
|
pubmed:abstractText |
Activated protein C resistance (APCR) is a common cause of familial thrombophilia and venous thrombosis. The aim of the study was to investigate the prevalence of APCR associated with factor V Leiden mutation and its relevance in comparison to other risk factors for thromboembolic disorders in women with a history of previous complicated pregnancies (history of fetal loss in the second and third trimester n = 34, preeclampsia n = 46). The frequency of APCR was significantly higher in women with a history of fetal loss and preeclampsia (23.5 and 26.1%, respectively) compared with a control group (3.8%). The prevalence of antithrombin, protein C and protein S deficiencies and the presence of antiphospholipid antibodies were also investigated: the prevalence of at least one disorder was 41.2% in the group with previous fetal loss, 37.0% in the group with previous preeclampsia and 7.5% in the control group.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0301-0147
|
|
pubmed:author |
pubmed-author:AbbateRR,
pubmed-author:ChenF YFY,
pubmed-author:CioniRR,
pubmed-author:FediSS,
pubmed-author:La TorrePP,
pubmed-author:LucchettiRR,
pubmed-author:MartiniEE,
pubmed-author:MecacciFF,
pubmed-author:MelliAA,
pubmed-author:ParrettiEE,
pubmed-author:PepeGG,
pubmed-author:PriscoDD
|
|
pubmed:copyrightInfo |
Copyright 2000 S. Karger AG, Basel
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
29
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
197-203
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10702700-Activated Protein C Resistance,
pubmed-meshheading:10702700-Adult,
pubmed-meshheading:10702700-Antibodies, Anticardiolipin,
pubmed-meshheading:10702700-Antithrombins,
pubmed-meshheading:10702700-Blood Coagulation Disorders,
pubmed-meshheading:10702700-European Continental Ancestry Group,
pubmed-meshheading:10702700-Factor V,
pubmed-meshheading:10702700-Family Health,
pubmed-meshheading:10702700-Female,
pubmed-meshheading:10702700-Fetal Death,
pubmed-meshheading:10702700-Hemostatics,
pubmed-meshheading:10702700-Humans,
pubmed-meshheading:10702700-Italy,
pubmed-meshheading:10702700-Lupus Coagulation Inhibitor,
pubmed-meshheading:10702700-Mass Screening,
pubmed-meshheading:10702700-Matched-Pair Analysis,
pubmed-meshheading:10702700-Point Mutation,
pubmed-meshheading:10702700-Pre-Eclampsia,
pubmed-meshheading:10702700-Pregnancy,
pubmed-meshheading:10702700-Pregnancy Complications,
pubmed-meshheading:10702700-Pregnancy Trimesters,
pubmed-meshheading:10702700-Prevalence,
pubmed-meshheading:10702700-Protein C Deficiency,
pubmed-meshheading:10702700-Protein S Deficiency,
pubmed-meshheading:10702700-Risk Factors,
pubmed-meshheading:10702700-Thrombophilia
|
|
pubmed:year |
1999
|
|
pubmed:articleTitle |
Usefulness of screening for congenital or acquired hemostatic abnormalities in women with previous complicated pregnancies.
|
|
pubmed:affiliation |
Institute of Obstetrics and Gynaecology, University of Florence, Italy.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study
|
