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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2000-4-28
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pubmed:abstractText |
Strain variations of Helicobacter pylori have been tested by numerous methods and compared among different patient groups. The aim of this study was to investigate whether H. pylori expresses disease-specific proteins that can be detected by two-dimensional polyacrylamide gel electrophoresis (2-D PAGE). H. pylori strains isolated from duodenal ulcer, gastric cancer, and gastritis patients were analyzed. Extensive variation in spot patterns was observed between the strains, but a dendrogram analysis revealed that some strains within each disease group clustered together. Eight proteins were sequenced and found in the H. pylori genome sequence. 2-D PAGE is a useful method for studies of protein expression and for highlighting the extensive strain variation that H. pylori exhibits.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-10215569,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-10381913,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-1400229,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-1459105,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-14907713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-1915251,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-1916229,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-2807540,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-3309143,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-7481525,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-7534278,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-7569989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-8003937,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-8050994,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-8509328,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-8780568,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-8793879,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-8962108,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-9100641,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-9163902,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-9514929,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-9570115,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-9590411,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-9731985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10702510-9952230
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1071-412X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
301-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:10702510-Adenocarcinoma,
pubmed-meshheading:10702510-Bacterial Proteins,
pubmed-meshheading:10702510-Duodenal Ulcer,
pubmed-meshheading:10702510-Electrophoresis, Gel, Two-Dimensional,
pubmed-meshheading:10702510-Gastritis,
pubmed-meshheading:10702510-Helicobacter pylori,
pubmed-meshheading:10702510-Humans,
pubmed-meshheading:10702510-Immunoblotting,
pubmed-meshheading:10702510-Sequence Analysis,
pubmed-meshheading:10702510-Stomach Neoplasms
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pubmed:year |
2000
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pubmed:articleTitle |
Clustering of clinical strains of Helicobacter pylori analyzed by two-dimensional gel electrophoresis.
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pubmed:affiliation |
Department of Medical Epidemiology, Karolinska Institute, Stockholm, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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