rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
9204
|
pubmed:dateCreated |
2000-3-22
|
pubmed:abstractText |
Susceptibility to disease after infection by Mycobacterium tuberculosis is influenced by environmental and host genetic factors. Vitamin D metabolism leads to activation of macrophages and restricts the intracellular growth of M. tuberculosis. This effect may be influenced by polymorphisms at three sites in the vitamin D receptor (VDR) gene. We investigated the interaction between serum vitamin D (25-hydroxycholecalciferol) concentrations and VDR genotype on susceptibility to tuberculosis.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0140-6736
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
19
|
pubmed:volume |
355
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
618-21
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10696983-Calcifediol,
pubmed-meshheading:10696983-Case-Control Studies,
pubmed-meshheading:10696983-Diet, Vegetarian,
pubmed-meshheading:10696983-Emigration and Immigration,
pubmed-meshheading:10696983-Female,
pubmed-meshheading:10696983-Humans,
pubmed-meshheading:10696983-Incidence,
pubmed-meshheading:10696983-India,
pubmed-meshheading:10696983-London,
pubmed-meshheading:10696983-Male,
pubmed-meshheading:10696983-Middle Aged,
pubmed-meshheading:10696983-Mycobacterium tuberculosis,
pubmed-meshheading:10696983-Polymorphism, Genetic,
pubmed-meshheading:10696983-Receptors, Calcitriol,
pubmed-meshheading:10696983-Tuberculosis,
pubmed-meshheading:10696983-Vitamin D Deficiency
|
pubmed:year |
2000
|
pubmed:articleTitle |
Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study.
|
pubmed:affiliation |
Division of Infectious Diseases, Case Western Reserve University, Cleveland, OH, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|