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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2000-3-13
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pubmed:abstractText |
Internal anal sphincterotomy for treating chronic anal fissure can irreversibly damage anal continence. Reversible chemical sphincterotomy may be achieved by anal application of glyceryl trinitrate ointment (nitric oxide donor), which has been reported to heal the majority of patients with anal fissure by inducing sphincter relaxation and improving anodermal blood flow. This trial aimed to further clarify the role of glyceryl trinitrate in the treatment of chronic anal fissure.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0012-3706
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pubmed:author |
pubmed-author:AltomareD FDF,
pubmed-author:ArcanàFF,
pubmed-author:BottiniCC,
pubmed-author:LovreglioRR,
pubmed-author:MilitoGG,
pubmed-author:NardelliNN,
pubmed-author:PescatoriMM,
pubmed-author:Pulvirenti-D'UrsoAA,
pubmed-author:RinaldiMM,
pubmed-author:ScardignoDD,
pubmed-author:SpinelliFF
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pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
174-9; discussion 179-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10696890-Adult,
pubmed-meshheading:10696890-Anal Canal,
pubmed-meshheading:10696890-Blood Flow Velocity,
pubmed-meshheading:10696890-Chronic Disease,
pubmed-meshheading:10696890-Double-Blind Method,
pubmed-meshheading:10696890-Female,
pubmed-meshheading:10696890-Fissure in Ano,
pubmed-meshheading:10696890-Headache,
pubmed-meshheading:10696890-Humans,
pubmed-meshheading:10696890-Hypotension, Orthostatic,
pubmed-meshheading:10696890-Laser-Doppler Flowmetry,
pubmed-meshheading:10696890-Male,
pubmed-meshheading:10696890-Manometry,
pubmed-meshheading:10696890-Nitroglycerin,
pubmed-meshheading:10696890-Ointments,
pubmed-meshheading:10696890-Pain,
pubmed-meshheading:10696890-Pain Measurement,
pubmed-meshheading:10696890-Treatment Outcome,
pubmed-meshheading:10696890-Vasodilator Agents,
pubmed-meshheading:10696890-Wound Healing
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pubmed:year |
2000
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pubmed:articleTitle |
Glyceryl trinitrate for chronic anal fissure--healing or headache? Results of a multicenter, randomized, placebo-controled, double-blind trial.
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pubmed:affiliation |
Dipartimento di Emergenza e Trapianti d'Organo, Università di Bari, Italy.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Multicenter Study
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