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rdf:type |
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lifeskim:mentions |
umls-concept:C0003250,
umls-concept:C0016263,
umls-concept:C0054961,
umls-concept:C0175630,
umls-concept:C0205195,
umls-concept:C0205369,
umls-concept:C0229664,
umls-concept:C0332324,
umls-concept:C0815000,
umls-concept:C1334863,
umls-concept:C1413240
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pubmed:issue |
1
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pubmed:dateCreated |
2000-3-22
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pubmed:abstractText |
Intensive chemoradiotherapy followed by peripheral blood stem cell transplantation has been introduced to treat children with advanced neuroblastoma (NBL). Detection of NBL cells in peripheral blood (PB) is important to prevent reinfusion of NBL cells. Several immunologic methods have been proposed for detecting NBL cells in hematologic samples. The development of a sensitive and specific combination of monoclonal antibodies (MoAbs) for detecting small numbers of NBL cells in PB using flow cytometry remains an important challenge.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD45,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD56,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD81,
http://linkedlifedata.com/resource/pubmed/chemical/CD81 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Gangliosides,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/ganglioside, GD2
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pubmed:status |
MEDLINE
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pubmed:issn |
1077-4114
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
20-6
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:10695817-Adolescent,
pubmed-meshheading:10695817-Antibodies, Monoclonal,
pubmed-meshheading:10695817-Antigens, CD,
pubmed-meshheading:10695817-Antigens, CD45,
pubmed-meshheading:10695817-Antigens, CD56,
pubmed-meshheading:10695817-Antigens, CD81,
pubmed-meshheading:10695817-Child,
pubmed-meshheading:10695817-Child, Preschool,
pubmed-meshheading:10695817-Flow Cytometry,
pubmed-meshheading:10695817-Gangliosides,
pubmed-meshheading:10695817-Humans,
pubmed-meshheading:10695817-Infant,
pubmed-meshheading:10695817-Infant, Newborn,
pubmed-meshheading:10695817-Membrane Proteins,
pubmed-meshheading:10695817-Neoplastic Cells, Circulating,
pubmed-meshheading:10695817-Neuroblastoma,
pubmed-meshheading:10695817-Reference Values,
pubmed-meshheading:10695817-Sensitivity and Specificity
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pubmed:articleTitle |
A new sensitive and specific combination of CD81/CD56/CD45 monoclonal antibodies for detecting circulating neuroblastoma cells in peripheral blood using flow cytometry.
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pubmed:affiliation |
Division of Laboratory, Kanagawa Children's Medical Center, Yokohama, Japan.
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pubmed:publicationType |
Journal Article
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