Source:http://linkedlifedata.com/resource/pubmed/id/10692583
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2-3
|
| pubmed:dateCreated |
2000-4-3
|
| pubmed:abstractText |
We have isolated a novel opsin from the pineal complex of Atlantic salmon (Salmo salar) and from the brain of the puffer fish (Fugu rubripes). These extra-retinal opsins share approximately 74% identity at the nucleotide and amino acid level with rod-opsins from the retina of these species. By PCR, we have determined that the novel rod-like opsin is not expressed in the salmon retina, and the retinal rod-opsin is not expressed in the salmon pineal. Phylogenetic analysis suggests that the rod-like opsins arose from a gene duplication event approximately 205 million years ago, a time of considerable adaptive radiation of the bony fish. In view of the large differences in the coding sequences of the pineal/brain rod-like opsins, their extra-retinal sites of expression, and phylogenetic position we have termed these novel opsins 'extra-retinal rod-like opsins' (ERrod-like opsins). We speculate that the differences between retinal rod-opsins and ERrod-like opsins have arisen from their differing photosensory roles and/or genetic drift after the gene duplication event in the Triassic.
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| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0014-5793
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:day |
25
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| pubmed:volume |
468
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
181-8
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| pubmed:dateRevised |
2008-11-21
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| pubmed:meshHeading |
pubmed-meshheading:10692583-Amino Acid Sequence,
pubmed-meshheading:10692583-Animals,
pubmed-meshheading:10692583-Brain Chemistry,
pubmed-meshheading:10692583-Cattle,
pubmed-meshheading:10692583-Evolution, Molecular,
pubmed-meshheading:10692583-Fishes,
pubmed-meshheading:10692583-Gene Duplication,
pubmed-meshheading:10692583-Gene Library,
pubmed-meshheading:10692583-Molecular Sequence Data,
pubmed-meshheading:10692583-Photoreceptor Cells, Vertebrate,
pubmed-meshheading:10692583-Phylogeny,
pubmed-meshheading:10692583-Pineal Gland,
pubmed-meshheading:10692583-Retina,
pubmed-meshheading:10692583-Retinal Rod Photoreceptor Cells,
pubmed-meshheading:10692583-Rod Opsins,
pubmed-meshheading:10692583-Salmo salar,
pubmed-meshheading:10692583-Sequence Alignment,
pubmed-meshheading:10692583-Sequence Homology, Amino Acid,
pubmed-meshheading:10692583-Sharks,
pubmed-meshheading:10692583-Species Specificity
|
| pubmed:year |
2000
|
| pubmed:articleTitle |
A novel rod-like opsin isolated from the extra-retinal photoreceptors of teleost fish.
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| pubmed:affiliation |
Department of Biology, Sir Alexander Fleming Building, Imperial College of Science, Technology and Medicine, London, UK.
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|