rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2000-3-22
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pubmed:abstractText |
Radiation synovectomy is an effective treatment for chronic synovitis refractory to pharmacological treatment in patients with rheumatoid or seronegative arthritis. Concerns persist about possible radiation-induced cytogenetic damage after radiation synovectomy leading to recommendations to use this technique only in the elderly. Micronucleus (MN) frequency in lymphocytes and urinary excretion of 8-hydroxy-2'-deoxyguanosine (8OHdG) as an indicator of cellular oxidative DNA base damage are biomarkers of radiation-induced cytogenetic damage. The course of both biomarkers was studied in patients with different types of chronic synovitis undergoing radiation synovectomy with very short-lived 165Dy-ferric-hydroxide (DFH).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/8-hydroxy-2'-deoxyguanosine,
http://linkedlifedata.com/resource/pubmed/chemical/Deoxyguanosine,
http://linkedlifedata.com/resource/pubmed/chemical/Dysprosium,
http://linkedlifedata.com/resource/pubmed/chemical/Ferric Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulins,
http://linkedlifedata.com/resource/pubmed/chemical/Radioisotopes,
http://linkedlifedata.com/resource/pubmed/chemical/Technetium,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological,
http://linkedlifedata.com/resource/pubmed/chemical/ferric hydroxide,
http://linkedlifedata.com/resource/pubmed/chemical/technetium Tc 99m immunoglobulin
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0161-5505
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pubmed:author |
pubmed-author:AngelbergerPP,
pubmed-author:FloresJ AJA,
pubmed-author:GermadnikDD,
pubmed-author:HavlikEE,
pubmed-author:KvaternikHH,
pubmed-author:LangSS,
pubmed-author:PilgerAA,
pubmed-author:PirichCC,
pubmed-author:PrüfertUU,
pubmed-author:RüdigerH WHW,
pubmed-author:SchwameisEE,
pubmed-author:SinzingerHH,
pubmed-author:WanivenhausAA
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
250-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10688107-Adult,
pubmed-meshheading:10688107-Arthritis,
pubmed-meshheading:10688107-DNA Damage,
pubmed-meshheading:10688107-Deoxyguanosine,
pubmed-meshheading:10688107-Dysprosium,
pubmed-meshheading:10688107-Female,
pubmed-meshheading:10688107-Ferric Compounds,
pubmed-meshheading:10688107-Humans,
pubmed-meshheading:10688107-Immunoglobulins,
pubmed-meshheading:10688107-Knee Joint,
pubmed-meshheading:10688107-Male,
pubmed-meshheading:10688107-Radioisotopes,
pubmed-meshheading:10688107-Synovitis,
pubmed-meshheading:10688107-Technetium,
pubmed-meshheading:10688107-Tumor Markers, Biological
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pubmed:year |
2000
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pubmed:articleTitle |
Radiation synovectomy using 165Dy ferric-hydroxide and oxidative DNA damage in patients with different types of arthritis.
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pubmed:affiliation |
Department of Nuclear Medicine, Occupational Medicine, and Pathology, University of Vienna, Austria.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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