rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
1976-12-30
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pubmed:abstractText |
Hepatocellular necrosis in carbon tetracholride-induced injury of rats is associated with an accumulation of lipocytes (perisinusoidal cells or Ito cells) containing fat droplets and giving vitamin A fluorescence. In the subsequent formation of connective tissue septa, transitional cells having morphologic characteristics of lipocytes and fibroblasts are abundant and are associated with the appearance of type III collage-. The features suggest that the lipocyte is the precursor of the fibroblasts responsible for parenchymal fibrillogenesis and under these conditions forms type III collagen. The process is a postulated link between hepatocellular necrosis and fibrosis.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-1061156,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-1092488,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-1097805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-13026124,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-4336540,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-4350723,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-4365954,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-4416771,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-4421899,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-4599009,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-4924592,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-5076587,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-5600366,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1068482-5923468
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0027-8424
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3719-22
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1976
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pubmed:articleTitle |
Vitamin A-containing lipocytes and formation of type III collagen in liver injury.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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