|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007209,
umls-concept:C0033634,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0127400,
umls-concept:C0205314,
umls-concept:C0205369,
umls-concept:C0225880,
umls-concept:C0679622,
umls-concept:C0754680,
umls-concept:C1280500,
umls-concept:C1879547
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2000-3-8
|
|
pubmed:abstractText |
A new 1,4-benzothiazepine derivative, JTV519, has a strong protective effect against Ca(2+) overload-induced myocardial injury. We investigated the effect of JTV519 on ischemia/reperfusion injury in isolated rat hearts.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
1524-4539
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
22
|
|
pubmed:volume |
101
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
797-804
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:10683355-Animals,
pubmed-meshheading:10683355-Biological Transport,
pubmed-meshheading:10683355-Calcium Channel Blockers,
pubmed-meshheading:10683355-Enzyme Activation,
pubmed-meshheading:10683355-Isoenzymes,
pubmed-meshheading:10683355-Myocardial Ischemia,
pubmed-meshheading:10683355-Myocardial Reperfusion Injury,
pubmed-meshheading:10683355-Myocardium,
pubmed-meshheading:10683355-Protein Kinase C,
pubmed-meshheading:10683355-Protein Kinase C-delta,
pubmed-meshheading:10683355-Rats,
pubmed-meshheading:10683355-Thiazepines,
pubmed-meshheading:10683355-Ventricular Function, Left
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Anti-ischemic effect of a novel cardioprotective agent, JTV519, is mediated through specific activation of delta-isoform of protein kinase C in rat ventricular myocardium.
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|
pubmed:affiliation |
Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
|
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
