Linked Life Data

10682604

Source:http://linkedlifedata.com/resource/pubmed/id/10682604

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-4-20
pubmed:abstractText
The action potentials of ventricular myocardial cells were recorded with glass microelectrodes inside the cells from neonatal Wistar rats treated with selenomethionine and sodium selenite in concentrations of 1.0, 2.0, and 4.0 mg/L selenium. Both of selenomethionine and sodium selenite decreased the action potential parameters, such as action potential amplitude(APA), overshoot(OS), threshold potential(TP), maximum diastolic potential (MDP) and maximum rate of depolarization (Vmax). Selenomethionine decreased the action potential duration at 10%, 50% and 90% repolarization (APD10, APD50 and APD90), while sodium selenite prolonged APD10, APD50 and APD90 at dose of 4.0 mg/L selenium and decreased APD50 and APD90 at dose of 1.0 and 2.0 mg/L selenium. The results indicated that both sodium selenite and selenomethionine inhibit the transmembrane movement of Ca2- and sodium selenite also inhibits transmembrane movement of K+.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1000-8020
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
277-80
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
[Comparison between selenomethionine and sodium selenite on action potentials of cultured myocardiocytes].
pubmed:affiliation
Beijing Institute of Pharmacology and Toxicology, China.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract, Research Support, Non-U.S. Gov't