Linked Life Data

10681094

Source:http://linkedlifedata.com/resource/pubmed/id/10681094

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2000-2-24
pubmed:abstractText
A short-term evaluation of 6 months of estrogen therapy on oxidant status in 38 postmenopausal women was conducted. The levels of serum lipid peroxidation products, glutathione (GSH) status, and glutathione-related enzymes were evaluated before and after 6 months of hormone replacement therapy. After 6 months of estrogen treatment there was a significantly increased concentration of thiobarbituric acid-reactive substances (TBARS), which are an end product of lipid peroxidation. This was accompanied by a significant increase in the activity of glutathione peroxidase (GSH-Px). However, the activities of glutathione reductase (GSSG-R) and superoxide dismutase (SOD) were significantly decreased and total protein thiols were reduced. Data suggest that hormone replacement therapy in postmenopausal women is associated with oxidant mechanisms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1528-7394
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-5
pubmed:dateRevised
2006-2-16
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Effects of hormone replacement therapy on lipid peroxides and oxidation system in postmenopausal women.
pubmed:affiliation
Biochemistry Department, Cerrahpa?a Medical Faculty, University of Istanbul, Turkey.
pubmed:publicationType
Journal Article, Clinical Trial