Source:http://linkedlifedata.com/resource/pubmed/id/10680691
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2000-3-7
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pubmed:abstractText |
Despite their proven gains in signal-to-noise ratio and field-of-view for routine clinical MRI, phased-array detection systems are currently unavailable for nuclei other than protons (1H). A broadband phased-array system was designed and built to convert the 1H transmitter signal to the non-1H frequency for excitation and to convert non-1H phased-array MRI signals to the 1H frequency for presentation to the narrowband 1H receivers of a clinical whole-body 1.5 T MRI system. With this system, the scanner operates at the 1H frequency, whereas phased-array MRI occurs at the frequency of the other nucleus. Pulse sequences were developed for direct phased-array sodium (23Na) and phosphorus (31P) MRI of high-energy phosphates using chemical selective imaging, thereby avoiding the complex processing and reconstruction required for phased-array magnetic resonance spectroscopy data. Flexible 4-channel 31P and 23Na phased-arrays were built and the entire system tested in phantom and human studies. The array produced a signal-to-noise ratio improvement of 20% relative to the best-positioned single coil, but gains of 300-400% were realized in many voxels located outside the effective field-of-view of the single coil. Cardiac phosphorus and sodium MRI were obtained in 6-13 min with 16 and 0.5 mL resolution, respectively. Lower resolution human cardiac 23Na MRI were obtained in as little as 4 sec. The system provides a practical approach to realizing the advantages of phased-arrays for nuclei other than 1H, and imaging metabolites directly.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0740-3194
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
269-77
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10680691-Amplifiers, Electronic,
pubmed-meshheading:10680691-Artifacts,
pubmed-meshheading:10680691-Equipment Design,
pubmed-meshheading:10680691-Female,
pubmed-meshheading:10680691-Heart,
pubmed-meshheading:10680691-Humans,
pubmed-meshheading:10680691-Magnetic Resonance Imaging,
pubmed-meshheading:10680691-Magnetic Resonance Spectroscopy,
pubmed-meshheading:10680691-Male,
pubmed-meshheading:10680691-Myocardium,
pubmed-meshheading:10680691-Phosphorus,
pubmed-meshheading:10680691-Phosphorus Radioisotopes,
pubmed-meshheading:10680691-Sodium,
pubmed-meshheading:10680691-Sodium Isotopes,
pubmed-meshheading:10680691-Software
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pubmed:year |
2000
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pubmed:articleTitle |
A broadband phased-array system for direct phosphorus and sodium metabolic MRI on a clinical scanner.
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pubmed:affiliation |
Department of Radiology, Johns Hopkins University, Baltimore, Maryland 21287-0843, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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