Linked Life Data

10675917

Source:http://linkedlifedata.com/resource/pubmed/id/10675917

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2000-3-16
pubmed:abstractText
The principal neuronal types of the cerebral cortex are the excitatory pyramidal cells, which project to distant targets, and the inhibitory nonpyramidal cells, which are the cortical interneurones. This article reviews evidence suggesting that these two neuronal types are generated in distinct proliferative zones. Pyramidal cells are derived from the neuroepithelium in the cortical ventricular zone, and use the processes of radial glia in order to migrate and take their positions in the cortex in an 'inside-out' sequence. Relatively few nonpyramidal cells are generated in the cortical neuroepithelium: the majority is derived from the ganglionic eminence of the ventral telencephalon. These nonpyramidal neurones use tangential migratory paths to reach the cortex, probably travelling along axonal bundles of the developing corticofugal fibre system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0166-2236
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
126-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
The origin and migration of cortical neurones: new vistas.
pubmed:affiliation
Dept of Anatomy and Developmental Biology, University College London, London, UK WC1E 6BT.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't