Linked Life Data

10674436

Source:http://linkedlifedata.com/resource/pubmed/id/10674436

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2000-11-17
pubmed:abstractText
We have investigated the influence of age (3, 18, 24 months) on Thromboxane A2 (TXA2) and Prostacyclin (PGI2) levels in hippocampal slices from F344/NHSD rats. A significant increase in TXA2 and PGI2 levels was observed in 18 and 24 months old compared to 3 months old animals. A significant reduction in the ratio TXA2/PGI2 produced by a higher increase in PGI2 was observed in 24 month old animals. The reduction in the TXA2/PGI2 ratio has been related to vasodilatory and antiaggregating effects that may contribute to protect the brain against neuronal damage.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0197-4580
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
695-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Influence of aging on thromboxane A2 and prostacyclin levels in rat hippocampal brain slices.
pubmed:affiliation
Unitat de Farmacologia.IDIBAPS.(Institut d'Investigacions Biomèdiques August Pi I Sunyer) Facultat de Medicina, Universitat de Barcelona, Casanova, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't