Source:http://linkedlifedata.com/resource/pubmed/id/10674259
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
2000-3-6
|
| pubmed:abstractText |
Throughout 1996, 22 hospital-based laboratories in the Rhône-Alpes region of France collected pneumococcal strains and used a standardized protocol to record the following data; patient age and sex; type of specimen; and determination of susceptibility to at least the following antibiotics: oxacillin 1 microgram and 5 micrograms, erythromycin (Ery), tetracycline (Tet), chloramphenicol (Chl), rifampin (Rmp), and loracarbef. For penicillin-nonsusceptible strains (PNSSs), which were identified based on results with oxacillin, MICs for penicillin G, amoxicillin (Amx), and cefotaxime (Ctx) were determined using the E Test, at the study site and agar dilution at the coordinating center. Of the 1153 strains, 65.5% were from adults and 31.8% from children; patient age was unknown in 2.7% of cases. PNSPs (MIC > 0.06 mg/l) contributed 32.9% of strains (I: 23.3%; R: 9.6%) and were more common in children (41.1%) than in adults (28.1%). The frequency of PNSSs varied across specimen types: 27.9% in blood cultures (305 strains), 15.6% in cerebrospinal fluid (32), 38.7% in protected bronchopulmonary specimens (31), 31.5% in unprotected bronchopulmonary specimens (434), 50.8% in acute otitis media (118), and 34.4% in other specimens (221). Among PNSSs, nonsusceptibility (I + R) to other antibiotics was variable: Ery, 62.1%; Tet, 41.5%; Chl, 40.4%; Rmp, 1.1%. Corresponding figures for the overall strain population were Ery, 33.3%; Tet, 22.7%; Chl, 22.8%; Rmp, 0.9%. In addition, 56.5% of PNSSs exhibited multiple drug resistance. Resistance to amoxicillin (MIC > 2 mg/l) was demonstrated for only 5 strains. No strains were resistant to loracarbef or cefotaxime. Serotypes of the 379 PNSSs were as follows: 23F, 26.6%; 14 (25.6%); 9V (18.2%), 6 (8.7%), 15 (5%), 19 (4.5%).
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| pubmed:language |
fre
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0369-8114
|
| pubmed:author |
pubmed-author:AubertGG,
pubmed-author:BarbaCC,
pubmed-author:BlancRR,
pubmed-author:Boucaud-MaitreYY,
pubmed-author:BoyerMM,
pubmed-author:CarricajoAA,
pubmed-author:ChomaratMM,
pubmed-author:ClavierBB,
pubmed-author:ClergeauPP,
pubmed-author:DelubacFF,
pubmed-author:DumasMM,
pubmed-author:FevreDD,
pubmed-author:FuhrmannCC,
pubmed-author:GravagnatBB,
pubmed-author:LelievreHH,
pubmed-author:LetouzeyM NMN,
pubmed-author:MandjeeAA,
pubmed-author:MarteletPP,
pubmed-author:MelfiMM,
pubmed-author:Perrier-Gros-ClaudeJ DJD,
pubmed-author:ReverdyM EME,
pubmed-author:RosAA,
pubmed-author:RoureCC,
pubmed-author:ThierryJJ,
pubmed-author:TixierAA
|
| pubmed:issnType |
Print
|
| pubmed:volume |
47
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
N
|
| pubmed:pagination |
1060-4
|
| pubmed:dateRevised |
2010-2-17
|
| pubmed:meshHeading |
pubmed-meshheading:10674259-Adult,
pubmed-meshheading:10674259-Anti-Bacterial Agents,
pubmed-meshheading:10674259-Child,
pubmed-meshheading:10674259-Drug Resistance, Microbial,
pubmed-meshheading:10674259-Drug Resistance, Multiple,
pubmed-meshheading:10674259-Female,
pubmed-meshheading:10674259-France,
pubmed-meshheading:10674259-Humans,
pubmed-meshheading:10674259-Laboratories,
pubmed-meshheading:10674259-Male,
pubmed-meshheading:10674259-Microbial Sensitivity Tests,
pubmed-meshheading:10674259-Pneumococcal Infections,
pubmed-meshheading:10674259-Quality Assurance, Health Care,
pubmed-meshheading:10674259-Specimen Handling,
pubmed-meshheading:10674259-Streptococcus pneumoniae
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
[Pneumococcus observatory data in the Rhône-Alps region. Results from 1996].
|
| pubmed:affiliation |
Laboratoire de Biologie médicale, HIA Desgenettes, Lyon Armées, France.
|
| pubmed:publicationType |
Journal Article,
English Abstract,
Multicenter Study
|