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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2000-4-13
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pubmed:abstractText |
We examined the prophylactic effect of lafutidine, a novel histamine H(2)-receptor antagonist [(+/-)-2-(furfurylsulfinyl)-N-[4-[4-(piperidinomethyl)-2-pyr idyl]oxy- (Z)-2 butenyl]acetamide], on indomethacin-induced small intestinal ulcers in rats and investigated the relation of this action to capsaicin-sensitive sensory neurons.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/16,16-Dimethylprostaglandin E2,
http://linkedlifedata.com/resource/pubmed/chemical/Acetamides,
http://linkedlifedata.com/resource/pubmed/chemical/Ampicillin,
http://linkedlifedata.com/resource/pubmed/chemical/Capsaicin,
http://linkedlifedata.com/resource/pubmed/chemical/Histamine H2 Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Indomethacin,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Nos2 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Peroxidase,
http://linkedlifedata.com/resource/pubmed/chemical/Piperidines,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/lafutidine
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pubmed:status |
MEDLINE
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pubmed:issn |
0012-2823
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2000 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
39-46
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10671773-16,16-Dimethylprostaglandin E2,
pubmed-meshheading:10671773-Acetamides,
pubmed-meshheading:10671773-Ampicillin,
pubmed-meshheading:10671773-Animals,
pubmed-meshheading:10671773-Capsaicin,
pubmed-meshheading:10671773-Dose-Response Relationship, Drug,
pubmed-meshheading:10671773-Duodenal Ulcer,
pubmed-meshheading:10671773-Histamine H2 Antagonists,
pubmed-meshheading:10671773-Indomethacin,
pubmed-meshheading:10671773-Intestinal Mucosa,
pubmed-meshheading:10671773-Male,
pubmed-meshheading:10671773-Neurons, Afferent,
pubmed-meshheading:10671773-Nitric Oxide Synthase,
pubmed-meshheading:10671773-Nitric Oxide Synthase Type II,
pubmed-meshheading:10671773-Peroxidase,
pubmed-meshheading:10671773-Piperidines,
pubmed-meshheading:10671773-Pyridines,
pubmed-meshheading:10671773-Rats,
pubmed-meshheading:10671773-Rats, Sprague-Dawley
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pubmed:year |
2000
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pubmed:articleTitle |
Protective effect of lafutidine against indomethacin-induced intestinal ulceration in rats: relation to capsaicin-sensitive sensory neurons.
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pubmed:affiliation |
Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Misasagi, Yamashina, Kyoto, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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