|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2000-3-8
|
|
pubmed:abstractText |
Genetic polymorphisms of human cytochrome P450s have been implicated to be of importance for susceptibility to different cancers. Recently, a point mutation was found in the exon 2 of the CYP2E1 gene (CYP2E1*2) [Hu et al. 1997]. In order to evaluate a possible link between the point mutation in exon 2 of the CYP2E1 gene and the susceptibility to renal cell/urothelial cancer, we developed a screening method based on the polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP).
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0946-1965
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
38
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
30-4
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:10667834-Base Sequence,
pubmed-meshheading:10667834-Carcinoma, Renal Cell,
pubmed-meshheading:10667834-Cytochrome P-450 CYP2E1,
pubmed-meshheading:10667834-Exons,
pubmed-meshheading:10667834-Genetic Predisposition to Disease,
pubmed-meshheading:10667834-Genetic Testing,
pubmed-meshheading:10667834-Humans,
pubmed-meshheading:10667834-Kidney Neoplasms,
pubmed-meshheading:10667834-Point Mutation,
pubmed-meshheading:10667834-Polymerase Chain Reaction,
pubmed-meshheading:10667834-Polymorphism, Genetic,
pubmed-meshheading:10667834-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:10667834-Urologic Neoplasms
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Analysis of point mutation in exon 2 of CYP2E1 gene in renal cell/urothelial cancer patients in comparison with control population.
|
|
pubmed:affiliation |
Institute of Clinical Pharmacology, Jena, Germany.
|
|
pubmed:publicationType |
Journal Article
|
