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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2000-11-3
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pubmed:abstractText |
Transforming growth factor beta (TGF-beta) is an immunosuppressive cytokine which can induce immunoglobulin A (IgA) switch and Epstein-Barr virus (EBV) replication in latently infected cells. Here we report elevated serum levels of TGF-beta in various EBV-associated diseases correlating positively with EBV-specific IgA titers and negatively with IgM titers, suggesting a role for this cytokine in the pathogenesis of these diseases.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-10404092,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-1312750,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-1319842,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-1323899,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-1850382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-2580110,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-2848624,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-2999604,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-3027115,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-3030769,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-7489351,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-7513247,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-7543740,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-7565411,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-7585049,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-7636223,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-7761852,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-7769680,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-8016105,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-8206684,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-8386517,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-8808050,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-9094310,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-9378987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-9597127,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10666277-9761116
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
74
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2443-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
2000
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pubmed:articleTitle |
Elevated serum transforming growth factor beta1 levels in Epstein-Barr virus-associated diseases and their correlation with virus-specific immunoglobulin A (IgA) and IgM.
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pubmed:affiliation |
Laboratory of Immunovirology, Pediatric Research Center and Department of Microbiology & Immunology, University of Montreal and Sainte-Justine Hospital, Montreal, Quebec, Canada.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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