|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2000-3-16
|
|
pubmed:abstractText |
A total of 115 strains of herpes simplex virus were isolated from clinical material collected in patients with genital herpes. The majority (93%) of isolated strains were sensitive to acyclovir: ID50 varied from 0.15 to 0.80 microgram/ml acyclovir. Eleven (7%) strains from 4 patients were resistant to acyclovir: ID50 was 30-125 times higher in comparison with the reference HSV-1 strain L2.
|
|
pubmed:language |
rus
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0507-4088
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
44
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
247-9
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10665057-Acyclovir,
pubmed-meshheading:10665057-Animals,
pubmed-meshheading:10665057-Antiviral Agents,
pubmed-meshheading:10665057-Cercopithecus aethiops,
pubmed-meshheading:10665057-Drug Resistance, Microbial,
pubmed-meshheading:10665057-Female,
pubmed-meshheading:10665057-Herpes Genitalis,
pubmed-meshheading:10665057-Humans,
pubmed-meshheading:10665057-Male,
pubmed-meshheading:10665057-Simplexvirus,
pubmed-meshheading:10665057-Vero Cells
|
|
pubmed:articleTitle |
[Isolation of acyclovir-resistant strains of herpes simplex virus from clinical material].
|
|
pubmed:publicationType |
Journal Article,
English Abstract
|
