Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2000-3-17
pubmed:abstractText
The chlorate-resistant mutant cr88 is defective in photomorphogenesis, as shown by the phenotypes of long hypocotyls in red light and yellow cotyledons under all light conditions. A subset of light-regulated genes is expressed at subnormal levels in cr88. To analyze further the role that CR88 plays in photomorphogenesis, we investigated the genetic interactions between cr88 and mutants of two other loci affecting photomorphogenesis, CONSTITUTIVE PHOTOMORPHOGENIC1 (COP1) and LONG HYPOCOTYL5 (HY5). COP1 represses the expression of light-regulated genes in the dark, and HY5 inhibits hypocotyl elongation in the light. Using morphological, cellular, and gene expression criteria for epistasis analyses to position CR88 in the genetic hierarchy of the photomorphogenesis pathway, we determined that CR88 acts downstream of COP1 but in a branch separate from HY5. In the course of our analysis, we discovered that light causes extensive destruction of plastids in dark-grown cop1 seedlings and that cr88 prevents this destruction.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-10072396, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-10201077, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-10205059, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-11541207, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-1423630, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-1467650, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-16667294, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-16667505, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-16668164, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-2065972, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-2776216, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-7479759, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-7690685, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-7919990, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8038602, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8038603, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8058035, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8205001, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8313465, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8337753, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8364355, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8400877, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8439743, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8453299, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8535132, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8624438, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8653121, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8819865, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8893548, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-8919908, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9011090, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9014362, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9107042, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9165750, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9184203, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9367981, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9437868, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9477570, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9490750, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9596629, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9634578, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9659918, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9755158, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9808724, http://linkedlifedata.com/resource/pubmed/commentcorrection/10662857-9845368
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1040-4651
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
199-210
pubmed:dateRevised
2010-9-10
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Genetic interactions between the chlorate-resistant mutant cr 8 8 and the photomorphogenic mutants cop1 and hy5.
pubmed:affiliation
Department of Biological Sciences, University of Iowa, Iowa City, Iowa 52242, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.