|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2000-2-16
|
|
pubmed:abstractText |
Tyrosine kinase inhibition and tumor growth inhibition activity of verbascoside and homoplantaginin are described. Both molecules proved to be equally significant inhibitors of isolated EGF-R tyrosine kinases, nevertheless their in vitro antiproliferative activity was variable in cellular assays. Their different inhibitory efficacies could be interpreted on the basis of conformational analysis and lipophilicity evaluation.
|
|
pubmed:language |
hun
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0001-6659
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
69
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
232-9
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:10652790-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:10652790-Cell Division,
pubmed-meshheading:10652790-Cell Survival,
pubmed-meshheading:10652790-Flavonoids,
pubmed-meshheading:10652790-Glucosides,
pubmed-meshheading:10652790-Humans,
pubmed-meshheading:10652790-Molecular Conformation,
pubmed-meshheading:10652790-Phenols,
pubmed-meshheading:10652790-Plantago,
pubmed-meshheading:10652790-Plants, Medicinal,
pubmed-meshheading:10652790-Receptor, Epidermal Growth Factor,
pubmed-meshheading:10652790-Tumor Cells, Cultured
|
|
pubmed:year |
1999
|
|
pubmed:articleTitle |
[Biological activity and structure of antitumor compounds from Plantago media L].
|
|
pubmed:affiliation |
Eötvös Loránd Tudományegyetem, Növényszervezettani Tanszék, Budapest.
|
|
pubmed:publicationType |
Journal Article,
English Abstract
|
