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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2000-3-9
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pubmed:abstractText |
Dopamine (DA) is thought to regulate renal proximal transport through the inhibition of the Na+,K+-ATPase and/or Na+/H+ exchanger. Defects in this dopaminergic system are proposed to be a pathogenic factor of genetic hypertension. However, microperfusion studies have not consistently confirmed direct tubular effects of DA.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2,3,4,5-Tetrahydro-7,8-dihydroxy-1-p...,
http://linkedlifedata.com/resource/pubmed/chemical/8-((4-chlorophenyl)thio)cyclic-3',5'...,
http://linkedlifedata.com/resource/pubmed/chemical/Acetazolamide,
http://linkedlifedata.com/resource/pubmed/chemical/Adenylate Cyclase,
http://linkedlifedata.com/resource/pubmed/chemical/Bicarbonates,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic AMP,
http://linkedlifedata.com/resource/pubmed/chemical/Diuretics,
http://linkedlifedata.com/resource/pubmed/chemical/Dopamine Agonists,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Parathyroid Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Dopamine D1,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium-Bicarbonate Symporters,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium-Potassium-Exchanging ATPase,
http://linkedlifedata.com/resource/pubmed/chemical/Thionucleotides
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
534-43
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:10652030-2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine,
pubmed-meshheading:10652030-Acetazolamide,
pubmed-meshheading:10652030-Adenylate Cyclase,
pubmed-meshheading:10652030-Animals,
pubmed-meshheading:10652030-Bicarbonates,
pubmed-meshheading:10652030-Biological Transport,
pubmed-meshheading:10652030-Carrier Proteins,
pubmed-meshheading:10652030-Cyclic AMP,
pubmed-meshheading:10652030-Diuretics,
pubmed-meshheading:10652030-Dopamine,
pubmed-meshheading:10652030-Dopamine Agonists,
pubmed-meshheading:10652030-Enzyme Inhibitors,
pubmed-meshheading:10652030-Female,
pubmed-meshheading:10652030-Hydrogen-Ion Concentration,
pubmed-meshheading:10652030-Hypertension, Renal,
pubmed-meshheading:10652030-Kidney Tubules, Proximal,
pubmed-meshheading:10652030-Male,
pubmed-meshheading:10652030-Parathyroid Hormone,
pubmed-meshheading:10652030-Rabbits,
pubmed-meshheading:10652030-Rats,
pubmed-meshheading:10652030-Rats, Inbred SHR,
pubmed-meshheading:10652030-Rats, Inbred WKY,
pubmed-meshheading:10652030-Receptors, Dopamine D1,
pubmed-meshheading:10652030-Second Messenger Systems,
pubmed-meshheading:10652030-Sodium,
pubmed-meshheading:10652030-Sodium-Bicarbonate Symporters,
pubmed-meshheading:10652030-Sodium-Potassium-Exchanging ATPase,
pubmed-meshheading:10652030-Thionucleotides
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pubmed:year |
2000
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pubmed:articleTitle |
Dopamine inhibits renal Na+:HCO3- cotransporter in rabbits and normotensive rats but not in spontaneously hypertensive rats.
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pubmed:affiliation |
Department of Nephrology and Endocrinology, and Department of Infectious Diseases, Faculty of Medicine, University of Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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