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pubmed-article:10651518rdf:typepubmed:Citationlld:pubmed
pubmed-article:10651518lifeskim:mentionsumls-concept:C0005574lld:lifeskim
pubmed-article:10651518lifeskim:mentionsumls-concept:C0162557lld:lifeskim
pubmed-article:10651518pubmed:issue3 Suppl 3lld:pubmed
pubmed-article:10651518pubmed:dateCreated2000-1-24lld:pubmed
pubmed-article:10651518pubmed:abstractTextOrthotopic liver transplantation survival for patients with acute liver failure is poor (50%). Mortality on the waiting list is high due to the lack of donors. For these reasons, the possibility of sustaining hepatic function by extra-corporeal liver perfusion must be considered. In this experimental research, two groups of pigs have been submitted to total de-vascularisation of the liver causing acute hepatic failure. In the first group (4 pigs) no extra-corporeal assistance has been used after total de-vascularisation. All pigs died between 16 and 33 hours after the acute hepatic failure was induced. In the second group (8 pigs) after complete hepatic de-vascularisation an extra-corporeal hepatic support by continuous allo-perfusion of isolated liver was performed using the Abouna-Costa extra-corporeal circuit. All pigs were observed during the acute hepatic failure which lasted from 6.30 to 7.30 hours. The data that were more positively influenced by the extra-corporeal assistance were ammonia and lactates that improved after the application of hepatic assistance.lld:pubmed
pubmed-article:10651518pubmed:languageenglld:pubmed
pubmed-article:10651518pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
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pubmed-article:10651518pubmed:statusMEDLINElld:pubmed
pubmed-article:10651518pubmed:issn1121-8142lld:pubmed
pubmed-article:10651518pubmed:authorpubmed-author:RossiGGlld:pubmed
pubmed-article:10651518pubmed:authorpubmed-author:GattoIIlld:pubmed
pubmed-article:10651518pubmed:authorpubmed-author:FassatiL RLRlld:pubmed
pubmed-article:10651518pubmed:authorpubmed-author:PratoPPlld:pubmed
pubmed-article:10651518pubmed:authorpubmed-author:LathamLLlld:pubmed
pubmed-article:10651518pubmed:authorpubmed-author:CaccamoLLlld:pubmed
pubmed-article:10651518pubmed:authorpubmed-author:GiammarinaroG...lld:pubmed
pubmed-article:10651518pubmed:issnTypePrintlld:pubmed
pubmed-article:10651518pubmed:volume9lld:pubmed
pubmed-article:10651518pubmed:ownerNLMlld:pubmed
pubmed-article:10651518pubmed:authorsCompleteYlld:pubmed
pubmed-article:10651518pubmed:pagination67-73lld:pubmed
pubmed-article:10651518pubmed:dateRevised2003-11-14lld:pubmed
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pubmed-article:10651518pubmed:meshHeadingpubmed-meshheading:10651518...lld:pubmed
pubmed-article:10651518pubmed:articleTitleBiotechnologies and acute hepatic failure.lld:pubmed
pubmed-article:10651518pubmed:affiliationIstituto di Chirurgia Sperimentale e dei Trapianti, Università di Milano, Unità Operativa per il Trapianto e la Chirurgia del Fegato e del Polmone, Ospedale Maggiore IRCCS, Milano.lld:pubmed
pubmed-article:10651518pubmed:publicationTypeJournal Articlelld:pubmed